Obstructive Sleep Apnea and Sleep Architecture in Adolescents With Severe Obesity: Effects of a 9-Month Lifestyle Modification Program Based on Regular Exercise and a Balanced Diet

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine
Johanna RocheFabienne Mougin

Abstract

Physical exercise and lifestyle modification are recognized as adjunct therapy for obstructive sleep apnea (OSA) in overweight adults. The objectives of this study were to investigate the effects of long-term physical exercise combined with a balanced diet on sleep architecture, sleep duration, and OSA in adolescents with severe obesity. This interventional study was conducted in a nursing institution. Participants were aged 14.6 ± 1.2 years with obesity (body mass index (BMI) = 40.2 ± 6.5 kg/m2). At admission and at 9 months, participants underwent ambulatory polysomnography and incremental maximal exercise testing to determine cardiorespiratory fitness. Twenty-four subjects completed the study. Analyses were performed on the whole population and on a subgroup of subjects with OSA (OSA-subgroup). OSA, defined as obstructive apnea-hypopnea index (OAHI) ≥ 2 events/h, was diagnosed in 58.3% of the population. OAHI was only associated with fat mass in males (r = .75, P < .05). At 9 months postintervention, weight loss (-11.1 kg, P < .0001) and improved cardiorespiratory fitness (VO2peak: +4.9 mL/min/kg, P < .001) were found in the whole population. Sleep duration was increased (+34 minutes, P < .05) and sleep architecture was chan...Continue Reading

Citations

Feb 29, 2020·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Almudena Carneiro-BarreraGualberto Buela-Casal
Jun 15, 2019·Pediatric Pulmonology·Courtney M Quinlan, Ignacio E Tapia
Dec 17, 2018·Sleep & Breathing = Schlaf & Atmung·Orna SeverIris A Perez
Feb 23, 2019·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Johanna RocheFabienne Mougin
Jan 9, 2020·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Johanna RocheDavid Thivel
Oct 9, 2020·Journal of Sleep Research·Mariam M Ischander, Robert D Lloyd
Apr 3, 2020·Seminars in Pediatric Surgery·Michelle L KanneyRoberta M Leu
Feb 6, 2020·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Johanna RocheFabienne Mougin
Jul 27, 2021·Frontiers in Psychiatry·Nazar MazurakIsabelle Mack
Aug 26, 2021·World Journal of Otorhinolaryngology - Head and Neck Surgery·UNKNOWN Working group of Chinese guidelines for the diagnosis and treatment of childhood OSA;UNKNOWN Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery

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