Obstructive Sleep Apnea and Testosterone Deficiency

The World Journal of Men's Health
Sung Dong Kim, Kyu Sup Cho

Abstract

Obstructive sleep apnea (OSA) is a common disorder characterized by intermittent hypoxia and sleep fragmentation. OSA in middle-aged men is often associated with decreased testosterone secretion, together with obesity and aging. Although OSA treatment does not reliably increase testosterone levels in most studies, OSA treatment with testosterone replacement therapy (TRT) may not only improve hypogonadism, but can also alleviate erectile/sexual dysfunction. However, because TRT may exacerbate OSA in some patients, patients should be asked about OSA symptoms before and after starting TRT. Furthermore, TRT should probably be avoided in patients with severe untreated OSA.

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Citations

Mar 13, 2020·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Michael S IrwigIrina Bancos
Oct 17, 2019·European Endocrinology·Cornelius J FernandezJoseph M Pappachan
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Jul 9, 2020·Frontiers in Endocrinology·Sana SultanGeorgios K Dimitriadis
Feb 20, 2021·Annals of the American Thoracic Society·Grant A TurnerHeather M Strah

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