Obstructive sleep apnea syndrome (OSAS): Pathophysiology in Estonians

Pathophysiology : the Official Journal of the International Society for Pathophysiology
Marlit VeldiVeiko Vasar

Abstract

The aim of the study was to clarify the roles of age, obesity, smoking, alcohol, pathoanatomy and -physiology in Estonian's OSAS. For this 164 randomly chosen such patients were selected in different regions of Estonia. They underwent naso-oropharyngeal examination, physical examination of craniofacial abnormalities, and polysomnography. They also completed a self-reported questionnaire about smoking, alcohol use, excessive daytime sleepiness, hypertension, cardiac disorders, headaches, concentration disorders, and recurrent upper-airway diseases. The patients (129 men; 35 women) aged between 19 and 75 years (mean 47+/-12), BMI between 21 and 49 (mean 30.5+/-5.15), AHI between 5 and 105 (33+/-22). The results showed that there was a high percentage of naso-oropharyngeal disorders, such as: recurrent upper-airway diseases (54.2%), nasal breathing disorders (63.5%), and hypertrophy of tonsils (57%). There was also a high percentage of general characteristics, such as alcohol use (64%), excessive daytime sleepiness (85.5%), overweight (63%), and hypertension (51.2%). The regression summary for the dependent variable AHI if p-level=0.0042 (R=0.63347013) included age, BMI, hypertension, cardiac disorders, headaches, nasal obstructio...Continue Reading

References

Feb 26, 1998·American Journal of Respiratory and Critical Care Medicine·D FribergE Svanborg
May 31, 2001·Clinical Physiology·M VeldiA Vain
Jan 16, 2002·American Journal of Respiratory and Critical Care Medicine·Toshihide WatanabeTakashi Nishino
Apr 17, 2002·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marlit VeldiMart Kull
Jan 18, 2003·Sleep Medicine Reviews·Susan Redline, Peter V. Tishler
Nov 25, 2004·Pathophysiology : the Official Journal of the International Society for Pathophysiology·Marlit VeldiMart Kull
Jan 11, 2007·Sleep Medicine Reviews·E Lindberg, T Gislason

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Citations

Nov 30, 2010·Schizophrenia Research·Masanori SekimotoKiyohisa Takahashi
Jul 24, 2010·Headache·Dimos D MitsikostasDimitrios Papadopoulos

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