PMID: 32672713Jul 17, 2020Paper

OBTAINING OF BACTERIOCINES FROM BACTERIA BACILLUS SUBTILIS ATCC 6633 STRAIN BY ORIGINAL METHODS

Georgian Medical News
S Taghiyeva

Abstract

In recent years, bacteriocins were in the centre of scientific discussions. Nowadays it is considered that these biologically active substances could be an adequate replacement for classic synthetic antibiotics. They play an important role in the syntheses of various antimicrobial matters, such as disinfectants, pesticides, bacteriophages and so on. Being a product of the vital activity of bacteria, in nature these substances protect bacteria from bacteria-competitors. According to numerous scientific studies, they demonstrate bacteriostatic and bactericidal effects in vivo and in vitro. Moreover, they are safer for a macroorganism and the environment, and almost do not have side effects. Bacteriocins also do not cause sensibilisation and suppression of immunity. Due to their antibacterial effect, bacteriocins are already used in therapy (colibacterin, bifidumbacterin), veterinary medicine (nisin), food industry (bacteriocins of the Lactobacillus), and agriculture (phytolavin). Since just some bacteria secrets bacteriocins, the list of producer bacteria is relatively short. It was established that bacteria of the Genus Bacillus, in particular, Bacillus subtilis, possess such safety indicators and cultural properties that allow ...Continue Reading

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