Occlusion of seminal vesicles increases sexual activity in a mouse model

European Urology
Frédéric D BirkhäuserUrs E Studer

Abstract

Little is known about the physiologic role of seminal vesicles beyond their fertility function. It has been suggested repeatedly that seminal vesicles have an impact on sexual activity. Although this has been investigated in various animal models, such a role has never been found. To assess in a novel mouse model whether occlusion of seminal vesicles affects sexual activity. Adult male CD1 mice (n=77) were assigned randomly to the experimental groups: (1) seminal vesicle occlusion (SVO) (n=24), (2) seminal vesicle resection (SVR) (n=23), and (3) sham operation (SO) (n=30). Adult females were brought into estrus by the Whitten effect. After recuperation, mouse pairs were observed during sessions of 3h each. Sexual activity was analyzed separately by three observers blinded to the experimental conditions. SVO, SVR, and SO. The primary end point was percentage of sessions with intromission; secondary end points were number of intromissions and latency until first intromission. A logistic regression model and the Kruskal-Wallis test were used. A total of 141 sessions for a total of 423h were analyzed. Intromission was scored in 20 of 42 sessions (48%) with SVO mice, a significantly higher rate than the 8 of 39 sessions (21%) with S...Continue Reading

References

Apr 1, 1976·Behavioral Biology·D W Mosig, D A Dewsbury
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Aug 9, 1968·Science·W K WhittenJ A Greenstein
Dec 1, 1964·Journal of Reproduction and Fertility·R L LAWSON, A M SORENSEN
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May 12, 2010·Frontiers in Neuroendocrinology·P J BonthuisE F Rissman
Nov 6, 2010·The Journal of Sexual Medicine·Francois GiulianoKim Wallen

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Citations

Nov 21, 2015·World Journal of Urology·Bernhard KissGeorge N Thalmann
Jun 2, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Kazim SahinVijaya Juturu

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