Occult cancer in specimens of reduction mammaplasty aimed at symmetrization. A multicentric study of 2718 patients

The Breast : Official Journal of the European Society of Mastology
T SorinF Marchal

Abstract

Women who have undergone surgical treatment for breast cancer often benefit from a contralateral reduction mammaplasty (CRM) aimed at symmetrization of the contralateral breast unaffected by the initial cancer. In our 7-year multicentric study (12 centers) of 2718 patients, incidence of CRM cancers (CRMc) was 1.47% (n = 40) [95% CI 1.05%-2.00%]. The CRMc group had significantly more initial mammary cancers of invasive lobular carcinoma (ILC, 22.5% vs 12.0%) and ductal carcinoma in situ (DCIS, 35.0% vs 21.6%) types than the healthy CRM group (p = 0.017). 35.0% (n = 14) of patients had en bloc resection; 25.0% (n = 10) of surgical specimens were correctly oriented. En bloc resection and orientation of surgical specimens enable precise pinpointing of the CRMc. A salvage lumpectomy may be proposed as an option when margins are invaded. The histological distribution of the 40 CRMc (mean size 12.7 mm) was carcinoma in situ (CIS) 70%, ILC 12.5%, invasive ductal carcinoma (IDC) 12.5% and tubular carcinoma (TC) 5.0%.

References

Jan 1, 1993·Cancer·E RobinsonA I Neugut
Oct 1, 1996·British Journal of Plastic Surgery·O G TitleyM F Fatah
Sep 28, 2000·Plastic and Reconstructive Surgery·J D BoiceO Nyrén
Mar 1, 1960·Plastic and Reconstructive Surgery and the Transplantation Bulletin·R K SNYDERMAN, J G LIZARDO
Feb 26, 2005·Plastic and Reconstructive Surgery·Ivo PitanguyGiovanni André Pires Viana
Apr 12, 2005·Annales de chirurgie plastique et esthétique·M ColleauP Bonnier
Oct 7, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Amy K AldermanSteven J Katz
Jul 29, 2010·Breast Cancer Research and Treatment·Elrasheid A H KheirelseidMichael J Kerin
Feb 3, 2011·Plastic and Reconstructive Surgery·Sheri Slezak, Rachel Bluebond-Langner
Jun 1, 2011·Breast Cancer Research and Treatment·Amit GoyalChristopher M Caddy
Jul 11, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S P LynchA M Gonzalez-Angulo
Feb 18, 2014·Annales de chirurgie plastique et esthétique·T SorinG Dolivet

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Citations

Mar 26, 2016·Clinics in Plastic Surgery·Grant W Carlson
Oct 30, 2018·Aesthetic Surgery Journal·Cenk DemirdoverAdnan Menderes
Jul 19, 2019·Breast Cancer Research and Treatment·Rong TangKevin S Hughes
Sep 23, 2021·Plastic and Reconstructive Surgery·Seyed Amirhossein RazaviAlbert Losken

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