Occult colorectal polyps on CT colonography: implications for surveillance

AJR. American Journal of Roentgenology
Robert L MaccartyLynn A Wilson

Abstract

Our purpose was to determine the prevalence of polyps that are invisible on CT colonography (CTC) in a population previously screened for colorectal neoplasms. Differences in the prevalence of occult polyps in various populations might help explain the discordant reported sensitivities for polyp detection in published reports of CTC. Seventy-five consecutive patients who had been previously screened for polyps underwent same-day colonoscopy and CTC. Many of the patients had personal histories of previous polypectomies and were undergoing surveillance colonoscopy. The scans were interpreted prospectively by an experienced radiologist. Polyps missed prospectively on CTC were analyzed retrospectively by three experienced radiologists and categorized as perception errors (visible in retrospect), technical errors (e.g., obscured by feces or fluid), or occult (invisible). Thirty polyps 5 mm or larger were found at colonoscopy, 18 of which were missed prospectively on CTC. Of the 18 missed polyps, 12 could not be identified in retrospect, even though they were located in clean, dry, well-distended colonic segments. These were classified as occult. Ten of the 12 occult polyps showed flat morphology on review of colonoscopy video record...Continue Reading

Associated Clinical Trials

References

Oct 8, 1998·AJR. American Journal of Roentgenology·A H DachmanI Hanan
Nov 24, 1999·The New England Journal of Medicine·H M FenlonJ T Ferrucci
Aug 14, 2002·Abdominal Imaging·J L FidlerW S Harmsen
Sep 2, 2003·Gastroenterology·C Daniel JohnsonUNKNOWN American College of Radiology Imaging Network A6656
Nov 25, 2003·AJR. American Journal of Roentgenology·Jacob SosnaVassilios Raptopoulos
Dec 6, 2003·The New England Journal of Medicine·Perry J PickhardtWilliam R Schindler
Mar 16, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Jeremy R Jass
Mar 25, 2004·AJR. American Journal of Roentgenology·Thomas M GlueckerC Daniel Johnson
Apr 15, 2004·JAMA : the Journal of the American Medical Association·Peter B CottonHarold Butler
Jun 23, 2004·AJR. American Journal of Roentgenology·Michael MacariJames Babb
Oct 27, 2004·AJR. American Journal of Roentgenology·Perry J PickhardtWilliam R Schindler

❮ Previous
Next ❯

Citations

Jan 25, 2011·AJR. American Journal of Roentgenology·Lisa L ChuJudy Yee
Sep 26, 2013·AJR. American Journal of Roentgenology·Joel G FletcherC Daniel Johnson
Dec 13, 2006·Abdominal Imaging·C Y NioJ Stoker
Nov 28, 2012·Radiologic Clinics of North America·Perry J Pickhardt, David H Kim
Nov 13, 2010·Clinical Radiology·A IgnjatovicB P Saunders
Jul 27, 2010·Gastrointestinal Endoscopy Clinics of North America·Noriko SuzukiStuart A Taylor
May 11, 2010·Gastrointestinal Endoscopy Clinics of North America·Perry J Pickhardt, David H Kim
Mar 17, 2010·Academic Radiology·Perry J PickhardtJessica B Robbins
Dec 21, 2007·IEEE Transactions on Medical Imaging·Ender KonukogluSandy Napel
Mar 9, 2018·Abdominal Radiology·Perry J PickhardtC Daniel Johnson
Sep 30, 2009·Current Opinion in Gastroenterology·Perry J Pickhardt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.