Occult HBV infection in continuous ambulatory peritoneal dialysis and hemodialysis patients

Renal Failure
Tansu SavCengiz Utas

Abstract

Occult hepatitis B virus (HBV) infection can be defined as the presence of HBV DNA in the liver and/or blood in the absence of detectable serum hepatitis B surface antigen (HBs Ag). There is a high prevalence of occult HBV infection in dialysis patients. This study investigated the prevalence of occult HBV infection in continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis (HD) patients and compared the prevalence of occult HBV infection in dialysis patients either with or without hepatitis C virus (HCV) infection. In this cross-sectional study, 71 CAPD patients and 71 HD patients were evaluated. HBV DNA testing was performed by polymerase chain reaction (PCR). We recorded general characteristics of the patients, duration of dialysis, HBs Ag, antibody to hepatitis B surface antigen (anti-HBs), antibody to hepatitis B core antigen (anti-HBc), anti-HCV antibody (anti-HCV), HCV RNA, serum alanine aminotransferase (ALT), and aspartate aminotransferase levels (AST). Twelve (16.9%) of the 71 HD patients and seven (9.8%) of the 71 CAPD patients were HBV DNA-positive. A statistically significant difference was not observed in the groups. Anti-HCV was negative and AST and ALT levels were normal in all of the HBV-DNA positive ...Continue Reading

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Citations

Jul 26, 2012·Seminars in Immunopathology·Giovanni RaimondoTeresa Pollicino
Apr 8, 2011·World Journal of Gastroenterology : WJG·Maria Luisa Gutiérrez-GarcíaIngrid Buhigas-Garcia
Apr 8, 2011·World Journal of Gastroenterology : WJG·Miriam RomeroJavier García-Samaniego
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Oct 8, 2016·Advanced Biomedical Research·Hamid KalantariMajid Yaran
Aug 2, 2013·Memórias do Instituto Oswaldo Cruz·Cibele FranzCristiane Alves Villela-Nogueira
Jan 1, 2015·Journal of Translational Internal Medicine·Bassam Bernieh
Apr 2, 2020·Journal of Medical Virology·Sogol JamshidiKhadijeh Khanaliha

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