Occult hepatitis B in the genotype H-infected Nahuas and Huichol native Mexican population

Journal of Medical Virology
Sonia RomanArturo Panduro

Abstract

Mexico is considered to be a low endemic country for HBV infection. However, a high anti-HBc against a low hepatitis B surface antigen (HBsAg) seroprevalence is the reported characteristic of native Mexicans. HBV diagnosis and genotype distribution was examined in native populations (Nahuas and Huichol, n = 306), and compared to a non-native population (Mestizos, n = 17). Overall, 6% of the natives were positive for HBsAg and 33% had detectable anti-HBc. HBsAg prevalence was lower in Nahuas compared to Huichols (1.4% vs. 9.4%, P < 0.002). Occult hepatitis B was detected in 14.2% (41/289) of natives, who either tested positive (5.88%, 17/289 HBsAg-negative) or negative for anti-HBc marker (8%, 24/289 HBsAg-negative). Age-adjusted anti-HBc seroprevalence and HBsAg quantitation revealed a sub-optimal sensitivity of conventional immunoassays. Nahuas had HBV/H and Huichol had HBV/A as the predominant genotypes followed by genotypes D, C, B, A, and D, G and H, respectively. A less variable HBV/H was characteristic in Mestizos, compared to a much variable HBV/H identified among the Nahuas. In conclusion, these findings indicate a high HBV endemicity among native Mexican groups where occult B infection is common. The different distribu...Continue Reading

References

Jul 1, 1999·The New England Journal of Medicine·I CacciolaG Raimondo
Jun 30, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C BréchotP Paterlini-Bréchot
Jan 17, 2002·The American Journal of Tropical Medicine and Hygiene·M Cisneros-CastoloJ Escobedo-De La Peña
May 25, 2002·The Journal of General Virology·Karin Kidd-LjunggrenAlistair H Kidd
Aug 2, 2002·The Lancet Infectious Diseases·Michael Torbenson, David L Thomas
Sep 5, 2002·Archives of Virology·A QuinteroF H Pujol
Sep 5, 2002·Journal of Medical Virology·L V SánchezA Panduro
Dec 23, 2003·Intervirology·Yuzo Miyakawa, Masashi Mizokami
Feb 26, 2004·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·Jean-Pierre Allain
Oct 16, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gerald Y MinukCarla Osiowy
Feb 22, 2005·Journal of Viral Hepatitis·S Schaefer
May 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·Gabriel BedoyaAndrés Ruiz-Linares
Jul 11, 2006·Journal of Clinical Microbiology·Thoai Duong LyAnne-Marie Roque-Afonso
Aug 12, 2006·Human Biology·Dolores AcevesArturo Panduro
Nov 23, 2006·Journal of Hepatology·Giovanni RaimondoGiovanni Squadrito
Jan 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Teresa PollicinoGiovanni Raimondo
Feb 7, 2007·Virus Research·Marisol Devesa, Flor H Pujol
May 16, 2007·American Journal of Human Genetics·Alkes L PriceDavid Reich
Jan 9, 2008·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yukiko MiuraKatsunori Saigenji
Jan 17, 2008·The Journal of General Virology·Astrid ZahnJean-Pierre Allain
Mar 4, 2008·Journal of Hepatology·Giovanni RaimondoTeresa Pollicino
Mar 29, 2008·PLoS Genetics·Sijia WangAndrés Ruiz-Linares
Aug 22, 2008·Journal of Hepatology·Giovanni RaimondoFabien Zoulim

❮ Previous
Next ❯

Citations

Sep 12, 2013·World Journal of Gastroenterology : WJG·Sonia Roman, Arturo Panduro
Mar 25, 2014·World Journal of Gastroenterology : WJG·Norie YamadaTakanobu Kato
Apr 11, 2014·Viruses·Jaime Morales-RomeroRebeca García-Román
Dec 5, 2014·Virology Journal·Wilson Alfredo Rios-OcampoMaria-Cristina Navas
Mar 25, 2016·Diagnostic Microbiology and Infectious Disease·Eva MortensenMark Holodniy
Apr 24, 2014·Journal of Viral Hepatitis·H E RaoufT M Mansour
Mar 27, 2012·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Cecilia M DelfinoMirna M Biglione
Aug 8, 2014·Memórias do Instituto Oswaldo Cruz·Griselda Escobedo-MelendezSonia Roman
Nov 2, 2018·Human Vaccines & Immunotherapeutics·Hugo López-GatellCelia Alpuche-Aranda
Apr 8, 2015·World Journal of Hepatology·Catherine Mn CroaghSally J Bell
Apr 7, 2020·Transfusion Medicine·Pablo Hernández-RomanoNayali López-Balderas
Aug 28, 2020·Journal of Medical Virology·Jonas Michel WolfVagner Ricardo Lunge
Nov 18, 2015·World Journal of Gastroenterology : WJG·Rosa ZampinoNicola Coppola
Nov 12, 2015·World Journal of Gastroenterology : WJG·Omar Ramos-LopezArturo Panduro
Apr 3, 2014·Molecular Biology Reports·Elena Larrieta-CarrascoSamuel Canizales-Quinteros
Jul 7, 2017·Journal of Translational Internal Medicine·Rafael Torres-ValadezArturo Panduro
May 30, 2020·Environmental Science and Pollution Research International·Lorena Díaz de León-MartínezRogelio Flores-Ramírez
May 24, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Jonas Michel WolfVagner Ricardo Lunge
Aug 14, 2021·Revista de gastroenterología de México·F Higuera-de-la-TijeraE Wolpert-Barraza
Nov 2, 2019·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·David A Fernández-GalindoL V Sánchez-Orozco

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.