Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
S K LeeH-S Park

Abstract

Herb agents have been widely used for centuries in the Orient and they have been cultivated throughout Asia. There have been a few cases of occupational allergy caused by herb materials. We report a case of occupational asthma and rhinitis caused by six herb materials in a pharmacist working at a pharmacy. We sought the role of immediate hypersensitivity in herbal agent-induced asthma in a pharmacist. The patient had strong positive responses on skin prick test to extracts of six herb materials: Chunkung (Cnidii rhizoma), Banha (Pinellia ternata), Sanyak (Dioscorea radix), Kangwhal (Ostericum koreanum), Danggui (Angelica radix), and Kunkang (Zingiberis rhizoma). Bronchoprovocation tests showed an early asthmatic response to Danggui extract. Serum specific IgE antibodies to Chunkung, Banha, and Sanyak were detected by ELISA with no specific IgE bindings to Kangwhal, Danggui, and Kunkang extracts. Twelve percent sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and IgE immunoblotting revealed one IgE binding component (60 kD) within Chunkung extract, two (10, 25 kD) in Banha, and four (33, 34, 65, 98 kD) in Sanyak. Basophil histamine release test revealed that Danggui extract could release a greater amount of h...Continue Reading

References

Oct 1, 1975·The Journal of Allergy and Clinical Immunology·H ChaiR G Townley
Nov 1, 1991·The Journal of Allergy and Clinical Immunology·J SubizaE Subiza
Oct 1, 1989·The Journal of Allergy and Clinical Immunology·J A Price, J L Longbottom
Jun 1, 1994·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H S ParkH B Moon
Apr 1, 1996·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H S Park, D H Nahm
Feb 1, 1997·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·H S Park, D H Nahm
Oct 7, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C H SuhH Y Kim
Mar 11, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·H Y KimD C Choi
Apr 15, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H ParkY Kim

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Citations

Apr 20, 2002·Current Opinion in Allergy and Clinical Immunology·Jean-Luc Malo
Apr 4, 2013·Journal of the American Veterinary Medical Association·Rose D Nolen-WalstonElizabeth J Davidson
Aug 10, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Meihua JinHyeun Wook Chang
Dec 19, 2015·Environmental Health and Preventive Medicine·Ryoichi InabaMitsuhiro Nakamura
Jul 16, 2003·Allergy·B Niggemann, C Grüber
May 14, 2004·Thrombosis Research·Won-Hwan ParkCheorl-Ho Kim
Nov 10, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Kyungjin LeeHo-Young Choi
Feb 28, 2008·Journal of Korean Medical Science·Gyu-Young HurHae-Sim Park
Apr 26, 2008·Journal of Korean Medical Science·Kyung-Mook KimYou-Young Kim
Feb 18, 2005·Journal of Korean Medical Science·Hye-Kyung ParkYou-Young Kim
Jul 2, 2010·Allergy, Asthma & Immunology Research·You-Young Kim
Oct 24, 2012·Journal of the Chinese Medical Association : JCMA·Ying-Ying XuShui-Hong Zhou

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