PMID: 7336369Dec 1, 1981Paper

Occupational asthma caused by a plastics blowing agent, azodicarbonamide

Thorax
A J Slovak

Abstract

A prevalence study of occupational asthma was carried out by questionnaire in 1980 among a group of 151 workers who had been exposed to azodicarbonamide dust in the process of its manufacture. Twenty-eight (18.5%) people without previous asthma gave a history of episodes of late onset asthma after exposure to azodicarbonamide. Re-exposure caused repetition and worsening of symptoms. Immediate removal from further exposure resulted in rapid cessation of symptoms without further recurrence. Seven of 13 sensitised individuals who were still exposed three months after the onset of disease developed prolonged airways hyperreactivity to common environmental irritants. Azodicarbonamide should be excluded as a causative agent in plastics and rubber industry workers complaining of occupational asthma.

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Citations

Jan 1, 1991·American Journal of Industrial Medicine·J A Lee
Aug 1, 1986·Clinical Reviews in Allergy·A I Terr
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Apr 20, 2005·Occupational and Environmental Medicine·P J NicholsonC Boyle
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Sep 28, 2012·Journal of Occupational Medicine and Toxicology·Xaver BaurHenning Vellguth
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Jul 14, 2000·American Journal of Industrial Medicine·V van KampenX Baur
May 1, 1988·Journal of the Royal Society of Medicine·D M Smith

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