Occupational asthma due to exposure to iroko wood dust

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Luisa RicciardiStefania Isola

Abstract

Occupational asthma (OA) from iroko wood has been reported primarily in case reports. To improve understanding of the pathogenesis of OA induced by iroko wood dust. Three groups of woodworkers were included in this study: 9 workers who had clinically proven OA from iroko; 10 asymptomatic woodworkers; and 10 woodworkers with asthma. All patients underwent the following tests: a skin test with an iroko aqueous extract, specific IgE determination, and an iroko bronchial provocation test (IBPT). An eosinophil count was determined before and after the IBPT, and a methacholine inhalation test was performed after avoidance of exposure to iroko. Patients were asked to monitor their peak expiratory flow rates during a week at work followed by a week's vacation. In all patients with a personal history predictive of OA from iroko, a reduction of the peak expiratory flow rate and positivity to the IBPT while working with iroko were present. The latter test result showed a dual response, with a decrease in forced expiratory volume in 1 second from 25% to 32% at 10 minutes and a further decrease from 35% to 43% at 8 hours; at 24 hours, the eosinophil count was higher (P = .046). In 4 patients, the intradermal test results with iroko extract ...Continue Reading

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Citations

Apr 20, 2005·Occupational and Environmental Medicine·P J NicholsonC Boyle
Jun 19, 2013·Journal of Occupational Medicine and Toxicology·Tor B AasenUNKNOWN EOM Society
Oct 21, 2006·Journal of Occupational Health·Kimiko TomiokaYoko Kataoka
Oct 15, 2011·The Journal of Allergy and Clinical Immunology·Paloma CampoMiguel Blanca
Oct 21, 2015·Occupational Medicine·R E WiggansC M Barber
May 21, 2014·International Journal of Occupational Medicine and Environmental Health·Patrycja Krawczyk-SzulcJolanta Walusiak-Skorupa

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