Abstract
Garlic dust has not been a frequently encountered cause of IgE-mediated disease. We report on 12 patients (all of them garlic workers) with the clinical criteria for occupational asthma. Skin prick tests and serum-specific IgE determinations were performed with common inhalants, garlic, and other members of the Liliaceae family (onion, leek, and asparagus). Bronchial challenge test with garlic powder was performed in all patients. Garlic and onion extract proteins were separated by sodium dodecylsulfate-polyacrylamide gel electrophoresis. Immunoblot and IgE immunoblot inhibition analyses were performed with patients' sera on extracts of garlic, onion, and pollens of Phleum pratense and Chenopodium album. Garlic sensitization was demonstrated by bronchial challenge test in seven patients (group 1) and ruled out in the remaining five (group 2). Clinical data were similar in both groups. The patients with garlic allergy had a mean age of 27 years, and all of them had pollen allergy; sensitization to other members of the Liliaceae family was also common. Electrophoresis of garlic extract revealed two major protein bands at approximately 12 and 54 kd. During IgE immunoblotting, the pool of sera reacted with garlic proteins mainly at...Continue Reading
Citations
Jan 10, 2004·The Journal of Allergy and Clinical Immunology·Shao-Hsuan KaoLu-Ping Chow
Feb 10, 2004·The Journal of Allergy and Clinical Immunology·Juliane RiekerBernhard Homey
Mar 10, 2004·The Journal of Allergy and Clinical Immunology·Anna Nowak-WegrzynHugh A Sampson
Jul 25, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Juan-Carlos MirallesJosé-María Negro
Apr 27, 2000·Allergy·J C MirallesA Pascual
Feb 13, 2001·Allergy·P CadotJ L Ceuppens
Nov 6, 2004·International Archives of Allergy and Immunology·Isabella Schöll, Erika Jensen-Jarolim
Feb 24, 2009·Clinical and Molecular Allergy : CMA·Daniel A Ramirez, Sami L Bahna
Mar 4, 2005·Mycoses·Stephen R Davis
Feb 26, 2004·Allergy·F FerreiraA Mari
Jan 15, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A I TabarG Salcedo
Feb 19, 2008·Contact Dermatitis·John P McFaddenIan Kimber
Aug 3, 2006·Acta Clinica Belgica·D G EboW J Stevens
Dec 8, 2004·Immunology and Allergy Clinics of North America·Jonathan M Spergel, Joel Fiedler
Oct 6, 2007·Molecular Nutrition & Food Research·Francesca BorrelliAngelo A Izzo
Apr 4, 2015·Allergology International : Official Journal of the Japanese Society of Allergology·Tomoko KobayashiRyoji Tsuboi
Jan 27, 2004·The Annals of Pharmacotherapy·José O RiveraArmando González Stuart
Oct 25, 2002·Allergologia et immunopathologia·A Jiménez-TimonR Cobo López
Apr 26, 2000·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M AliM Afzal