PMID: 2111158Mar 1, 1990Paper

Occupational cadmium exposure and testicular endocrine function

Human & Experimental Toxicology
H J Mason

Abstract

Cadmium is known to cause testicular necrosis in several animal species, although there is little data on its possible effects in humans. We have investigated the effect of occupational cadmium exposure on the pituitary-testicular endocrine axis, as measured by serum testosterone, luteinizing hormone (LH) and follicular-stimulating hormone (FSH), in a well-characterized population occupationally exposed to cadmium. Over 60% of all workers, who had been exposed to cadmium oxide fumes for longer than a year, in a single factory, since 1926, were studied. Integrated cadmium exposure estimates were constructed for each subject from atmospheric measurements, together with other available company data, and these exposure estimates were validated by in-vivo neutron activation analyses of liver cadmium burdens. The lack of testicular endocrine effects was in contrast to significant dose-related changes in renal glomerular and tubular function demonstrated in the same population.

References

Mar 1, 1979·Physics in Medicine and Biology·B J ThomasJ H Fremlin
Jan 1, 1978·Urological Research·T SengeF Neumann
Mar 26, 1988·Lancet·A G DavisonM C Scott
Dec 1, 1988·British Journal of Industrial Medicine·H J MasonM C Scott

❮ Previous
Next ❯

Citations

Jan 1, 1994·Acta Neuropathologica·J P ProviasL E Becker
Aug 14, 2003·Ecotoxicology and Environmental Safety·Jaqueline CalderónFernando Díaz-Barriga
Apr 10, 2002·Journal of Toxicology and Environmental Health. Part a·Xiangbin ZengQinhu Kong
May 3, 2012·Arhiv za higijenu rada i toksikologiju·Alica PizentTanja Živković
Feb 4, 2005·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Jasna JurasovićSpomenka Telisman
Sep 15, 2004·Environmental Research·Xiangbin ZengGunnar F Nordberg
May 1, 1991·Human & Experimental Toxicology·A J McGregor, H J Mason
May 1, 1996·Critical Reviews in Toxicology·S TasD Lison

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.