PMID: 6163731Jan 1, 1981Paper

Occupational exposure to hexachlorocyclohexane. II. Health conditions of chronically exposed workers

International Archives of Occupational and Environmental Health
H L BrassowG Lehnert

Abstract

Sixty male workers in a lindane (gamma-hexachlorocyclohexane)-producing factory were examined with regard to health in comparison with an external control group of 20 clerks. Case history, physical examination, neurologic status, and ECG revealed no significant differences between groups. However, the following significant differences in clinical-chemical blood tests were ascertained: higher polymorphonuclear leukocyte count, lower lymphocyte count, higher reticulocyte count, lower prothrombin (Quick's) test, and lower blood concentrations of creatinine and uric acid. No significant differences were observed in total red and white blood cell as well as platelet counts, hemoglobin content, the other counts of differential blood picture, gamma-GT, GOT, GPT, LDH, cholinesterase, triglycerides, cholesterol, and urea. In spite of a pronounced exposure to the alpha-, beta-, and gamma-isomers of hexachlorocyclohexane, no signs of severe impairment of health were observed; only small deviations in some laboratory tests were found having no pathologic significance. However, biological monitoring and health supervision of HCH-exposed workers should be carried out.

References

Jul 1, 1967·Archives of Environmental Health·I West
Mar 1, 1974·Archives of Environmental Health·A Mayersdorf, R Israeli
Jan 1, 1980·International Archives of Occupational and Environmental Health·K BaumannG Lehnert

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Citations

Jan 1, 1986·International Archives of Occupational and Environmental Health·B DietzeC Brückner
Jan 1, 1981·International Archives of Occupational and Environmental Health·S TomczakG Lehnert
Jul 24, 2001·Drugs·T C RoosD R Bickers
Sep 1, 1990·Archives of Environmental Contamination and Toxicology·M TeufelG von Oelsnitz
Apr 8, 2015·Journal of Toxicology and Environmental Health. Part a·Carmen FreireSergio Koifman
Jan 1, 1981·International Archives of Occupational and Environmental Health·K BaumannK Stapel
Jan 1, 1993·International Archives of Occupational and Environmental Health·S K NigamS K Kashyap

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