Occurrence and detection method evaluation of group B streptococcus from prenatal vaginal specimen in Northwest China

Diagnostic Pathology
Yun XieQi Wang

Abstract

Sensitive and efficient detection of Group B Streptococcus (GBS) colonization in pregnant women is essential for prescription of prophylaxis at the time of delivery as GBS is an opportunistic pathogen known to cause infant mortality. In this report, two studies were conducted on the methods of GBS detection in Shaanxi province, China, a region lacking data for GBS detection and occurrence. For Study 1, 100 GBS culture-positive vaginal swabs were collected from 1,567 pregnant women for evaluation by direct latex agglutination test. In Study 2, 200 GBS vaginal swabs were evaluated by three culture methods (sheep blood agar (SBA), Columbia colistin-nalidixic agar (CNA), and selective carrot broth (SCB)) followed by analysis using a latex agglutination test. GBS was detected in 6.4 % of specimens in Study 1 and 10.5 % of specimens in Study 2. The results of the latex agglutination test in both studies were accurate with samples exhibiting high to moderate GBS growth, but the accuracy declined for samples with low GBS growth. The evaluation of culture methods for GBS detection revealed the sensitivity of SCB (95.2 %, p = 0.004) was significantly higher than that of the SBA medium (57.1 %). The sensitivity reported for SCB (95.2 %) w...Continue Reading

References

Mar 1, 1987·Journal of Clinical Microbiology·E R WaldC Byers
Oct 16, 1999·Acta Paediatrica·K A KuruvillaA K Jana
Jan 9, 2001·Archives of Internal Medicine·A I NeugutR L Miller
May 8, 2008·JAMA : the Journal of the American Medical Association·Christina R PharesUNKNOWN Active Bacterial Core surveillance/Emerging Infections Program Network
Jun 24, 2010·Clinics in Perinatology·Jennifer R Verani, Stephanie J Schrag
Apr 24, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alemnew F DagnewSue Ann Costa Clemens
Oct 15, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·B LuX Lu
Jan 13, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Santiago ScassoClaudio G Sosa

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Citations

Nov 29, 2017·Journal of Clinical Pathology·Ana Mafalda PintoOlga Maria Lage
Mar 23, 2019·Microbiology Spectrum·Vanessa N Raabe, Andi L Shane
Jun 9, 2021·Pediatrics and Neonatology·Yao Zhu, Xin-Zhu Lin

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BETA
PCR

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SPSS

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