Occurrence and ecotoxicological risk assessment of non-steroidal anti-inflammatory drugs in South African aquatic environment: What is known and the missing information?

Chemosphere
Lawrence Mzukisi Madikizela, Somandla Ncube

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are medications used individually or as mixtures with other pharmaceuticals for the treatment of various illnesses. Their easy accessibility and high human consumption have resulted to their detection at high concentrations in South African water resources. In the present work, an extensive review of the occurrence and ecotoxicological risk assessment of NSAIDs in South African aquatic environment is provided. Reviewed literature suggested ibuprofen, naproxen, diclofenac, ketoprofen and fenoprofen as the most prominent NSAIDs in the South African aquatic environment. Among these NSAIDs, higher concentrations of ibuprofen are common in South African waters. As a result, this drug was found to pose high ecotoxicological risks towards the aquatic organisms with the highest risk quotients of 14.9 and 11.9 found for algae in surface water and wastewater, respectively. Like in other parts of the world, NSAIDs are not completely removed in wastewater treatment plants. Removal efficiencies below 0% due to higher concentrations of NSAIDs in wastewater effluents rather than influents were observed in certain instances. The detection of NSAIDs in sediments and aquatic plants could serve as th...Continue Reading

References

Apr 1, 1990·Annals of Emergency Medicine·J M KolodzikM G Angelos
Nov 17, 2009·Environmental Pollution·Won-Jin SimJeong-Eun Oh
Nov 26, 2011·Environmental Science and Pollution Research International·Athanasios S StasinakisNikolaos S Thomaidis
Oct 2, 2012·The Science of the Total Environment·Laura Ferrando-ClimentDamià Barceló
Oct 12, 2012·Environmental Monitoring and Assessment·K KomoriA Harada
Jul 9, 2013·Environmental Science and Pollution Research International·Govindaraj ShanmugamBabu Rajendran Ramaswamy
Aug 13, 2013·The Science of the Total Environment·Christina I KosmaTriantafyllos A Albanis
May 6, 2014·Environment International·Niina Vieno, Mika Sillanpää
Jul 17, 2014·Environmental Monitoring and Assessment·Foluso O Agunbiade, Brenda Moodley
Oct 30, 2014·Environmental Science and Pollution Research International·Luisa PatroleccoNicoletta Ademollo
Feb 25, 2015·Environmental Science and Pollution Research International·Solomon MatongoPatrick Ndungu
Apr 20, 2016·International Journal of Clinical Pharmacy·Willem P MeuwesenMarike Cockeran
Oct 23, 2016·Environment International·Linson LonappanRao Y Surampalli
Feb 22, 2017·Journal of Environmental Management·Lawrence Mzukisi MadikizelaLuke Chimuka
May 4, 2017·Environmental Science and Pollution Research International·Vanessa de Jesus GaffneyCristina Maria Martins Almeida
Jun 24, 2017·Environmental Monitoring and Assessment·Lawrence Mzukisi Madikizela, Luke Chimuka
Oct 1, 2017·The Science of the Total Environment·José Abraham Rivera-JaimesMiren López de Alda
May 2, 2018·The Science of the Total Environment·Lawrence Mzukisi MadikizelaLuke Chimuka
Jun 12, 2018·Marine Pollution Bulletin·Bénilde BonnefilleHélène Fenet
Oct 23, 2018·Environmental Science. Processes & Impacts·Matthew NkoomJianchao Liu
Nov 2, 2018·Environmental Science and Pollution Research International·Zama Emmaculate MbheleLawrence Mzukisi Madikizela
Oct 31, 2019·Journal of Environmental Management·Lawrence Mzukisi MadikizelaLuke Chimuka
Jun 11, 2020·International Journal of Environmental Research and Public Health·Sesethu VumazonkeNosiphiwe Patience Ngqwala
Jul 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Olufemi Temitope AdemoyegunAnthony Ifeanyi Okoh
Nov 9, 2020·Journal of Environmental Management·Isabel Martínez-AlcaláAgustin Lahora

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.