Occurrence and prognostic effect of cervical spine injuries and cervical artery injuries with concomitant severe head injury.

Acta neurochirurgica
Juho VehviläinenRahul Raj

Abstract

Blunt cerebrovascular injuries (BCVIs) and cervical spinal injuries (CSIs) are not uncommon injuries in patients with severe head injury and may affect patient recovery. We aimed to assess the independent relationship between BCVI, CSI, and outcome in patients with severe head injury. We identified patients with severe head injury from the Helsinki Trauma Registry treated during 2015-2017 in a large level 1 trauma hospital. We assessed the association between BCVI and SCI using multivariable logistic regression, adjusting for injury severity. Our primary outcome was functional outcome at 6 months, and our secondary outcome was 6-month mortality. Of 255 patients with a cervical spine CT, 26 patients (10%) had a CSI, and of 194 patients with cervical CT angiography, 16 patients (8%) had a BCVI. Four of the 16 BCVI patients had a BCVI-related brain infarction, and four of the CSI patients had some form of spinal cord injury. After adjusting for injury severity in multivariable logistic regression analysis, BCVI associated with poor functional outcome (odds ratio [OR] = 6.0, 95% CI [confidence intervals] = 1.4-26.5) and mortality (OR = 7.9, 95% CI 2.0-31.4). We did not find any association between CSI and outcome. We found that BCV...Continue Reading

References

Mar 1, 1975·Lancet·B Jennett, M Bond
Jun 1, 1992·Annals of Emergency Medicine·J WilliamsC Shufflebarger
Nov 24, 1999·The Journal of Trauma·W L BifflJ M Burch
Oct 26, 2001·JAMA : the Journal of the American Medical Association·I G StiellJ Worthington
Apr 30, 2003·Injury·Elaine K DrainerPhilip T Munro
Nov 11, 2003·The Journal of Trauma·C Clay CothrenJon M Burch
Jun 16, 2004·Archives of Surgery·John C MayberryGeorge C Velmahos
Nov 10, 2006·Injury·Thomas A Gennarelli, Elaine Wodzin
Jan 10, 2009·The Journal of Trauma·Deborah M SteinThomas M Scalea
Nov 26, 2010·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Marco CiapettiAdriano Peris
Jan 17, 2012·Journal of the American College of Surgeons·Randall W FranzJodi F Hartman
Dec 12, 2012·Journal of Neurosurgery·Christoph J GriessenauerMark R Harrigan
Feb 13, 2013·Nature Reviews. Neurology·Henrik ZetterbergKaj Blennow
Sep 12, 2013·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Rahul RajMarkus B Skrifvars
Jun 29, 2014·Clinical Neurology and Neurosurgery·George M GhobrialSrinivas Prasad
Jul 8, 2015·The Journal of Trauma and Acute Care Surgery·Margaret H LauermanDeborah M Stein
Mar 26, 2016·The Journal of Trauma and Acute Care Surgery·Charles P ShahanTimothy C Fabian
Oct 19, 2016·American Journal of Surgery·Andrea E GeddesErnest E Moore
Mar 5, 2017·Acta neurochirurgica·Tuomo ThesleffTeemu M Luoto
May 26, 2017·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·M HeinänenT Söderlund
Jul 27, 2017·Journal of Spine Surgery·Roozbeh ShafafyJaykar R Panchmatia
Dec 23, 2017·World Journal of Surgery·Christian D WeberUNKNOWN TraumaRegister DGU
Sep 5, 2018·The Journal of Bone and Joint Surgery. American Volume·Daniel G TobertAndrew J Schoenfeld
Oct 31, 2018·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Tor BrommelandElisabeth Jeppesen

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Citations

Sep 13, 2020·Acta neurochirurgica·Andreas K DemetriadesWilco C Peul
Nov 12, 2020·Acta neurochirurgica·Juho VehviläinenRahul Raj

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BETA
imaging techniques
sedation
dissections

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SPSS Statistics
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