PMID: 9660467Jul 11, 1998Paper

Occurrence and susceptibility to antibiotics of Shigella species in stools of hospitalized children with bloody diarrhea in Pakistan

The American Journal of Tropical Medicine and Hygiene
K KhalilG B Lindblom

Abstract

The aim of the present investigation was to study the frequency of Shigella spp. in patients with bloody diarrhea in Pakistan and the susceptibility of isolated Shigella to three antibiotics: ampicillin, cotrimoxazole and nalidixic acid. In addition, the frequency of Campylobacter and Salmonella was also determined. Stool samples (n = 152) were collected from 152 diarrheic children less than six years of age passing blood and mucus in their stools who were admitted to Paediatric Department of Mayo Hospital in Lahore, Pakistan from June to September 1990. The samples were cultivated on standard media for Shigella, Campylobacter, and Salmonella. Susceptibility of Shigella isolates was tested by disk diffusion method. The frequency of isolation was 19.1% for Shigella spp., 7.9% for Campylobacter, and 4.6% for Salmonella. Shigella flexneri (7.9%) was the most frequently isolated species, followed by S. dysenteriae (6.6%), S. boydii, (3.3%) and S. sonnei (1.3%). All Shigella isolates were susceptible to nalidixic acid (100%), while only a few were susceptible to cotrimoxazole (7.0%) and ampicillin (3.5%). In Pakistan, self-medication and purchases of drugs without a prescription are commonly practiced. Thus, there is a greater possi...Continue Reading

Citations

Feb 9, 2002·Environmental Health Perspectives·Ronnie B LevinEric G Reichard
Sep 15, 2007·Journal of Gastroenterology and Hepatology·Farid H Abu ElamreenJamal Elshikh Deeb
Feb 7, 2020·Folia Microbiologica·Iqbal NisaAnwar Ali
Jul 14, 2005·Expert Opinion on Drug Safety·Richard W Grady
Mar 20, 2013·BioMed Research International·Suvash Chandra OjhaKirnpal-Kaur Banga Singh
May 23, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mark R WallaceKenneth C Hyams
Oct 13, 2006·Current Opinion in Infectious Diseases·J A AdachiC D Ericsson
May 7, 1999·Environmental Health Perspectives·T E Ford

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