Occurrence of A-waves in F-wave studies of healthy nerves

Muscle & Nerve
Leena PuksaBjörn Falck

Abstract

A-waves are compound muscle action potentials that follow the M-wave with a constant shape and latency; usually they are detected during F-wave studies. A large reference value database for F-wave parameters from the median, ulnar, peroneal, and tibial nerves was collected from 121-196 subjects aged 14 to 95 years without known pathology involving the studied nerves. From this material, we studied retrospectively the occurrence of A-waves. To be included, an A-wave had to be clearly discriminated from the baseline in at least 8 of 20 traces with a jitter of less than 0.5 ms. A-waves occurred in 25% of the tibial nerves studied and 14% of the peroneal nerves but in only 2% of median and ulnar nerves. In the peroneal and tibial nerves, the frequency of A-waves increased with age, suggesting that A-waves may be related to normal age-related mild neuropathic changes of alpha motor neurons. Thus, A-waves are frequently found in lower-extremity nerves in healthy subjects and less commonly in upper-extremity nerves. Their presence must therefore be interpreted with caution and cannot be taken as necessarily indicative of abnormality.

References

Dec 1, 1996·Electroencephalography and Clinical Neurophysiology·C BischoffL Puksa
Mar 23, 1999·Muscle & Nerve·M E KornhuberB Conrad
Jul 7, 2000·Muscle & Nerve·J Rowin, M N Meriggioli
Jul 13, 2002·Muscle & Nerve·Satu LaaksonenBjörn Falck

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Citations

Jun 19, 2010·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ferdinando SartucciAlessandro Rossi
Aug 8, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C Pastore-OlmedoE Geijo-Barrientos
Jan 5, 2012·Neuroscience Letters·Mehmet Ugur CevikNebahat Tasdemir
Nov 8, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Shingo KawakamiTeruo Shimizu
Jul 27, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Josep Valls-SoleJoao Costa
Mar 26, 2016·Frontiers in Human Neuroscience·Jia FangQingyun Ding
Mar 22, 2008·Acta Neurologica Scandinavica·M A FisherK N Somashekar
Apr 3, 2012·Journal of the Peripheral Nervous System : JPNS·Emilio Geijo-BarrientosCarlos Pastore-Olmedo
Mar 21, 2012·Muscle & Nerve·Elisabeth ChroniErik Stålberg
Oct 25, 2013·Muscle & Nerve·Morris A Fisher
Jan 11, 2005·Neurophysiologie clinique = Clinical neurophysiology·F Mesrati, M F Vecchierini
Sep 8, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Steve VucicDidier Cros
Nov 24, 2017·Frontiers in Neurology·Viviana VersaceRaffaele Nardone
May 31, 2018·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Sindhuja LakshminarasimhanLakshminarasimhan Ranganathan
Sep 25, 2018·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Liborio RampelloAntonio Arcidiacono
Aug 23, 2017·Brain and Behavior·Iva SrotovaJosef Bednarik
Oct 30, 2020·Frontiers in Neurology·Qiong CaiXunhua Li

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