Occurrence of antibiotic residues and antibiotic-resistant bacteria in effluents of pharmaceutical manufacturers and other sources around Hanoi, Vietnam

The Science of the Total Environment
Phong K ThaiNguyen Thi Kieu Anh

Abstract

Pharmaceutical manufacturers in Vietnam are producing a wide variety of antibiotics for human and veterinary use. Consequently, the water discharged from those facilities can contain residues of antibiotics, which could have adverse impact on the environment. However, studies on the occurrence of antibiotics in the wastewater from pharmaceutical manufacturers in Vietnam are almost non-existent. In this study, water samples were collected at around the outlets of four pharmaceutical manufacturing plants as well as from a hospital and an aquaculture farm around Hanoi in 2016 and 2017. Fifteen antibiotics from four major classes (β-lactam, quinolones, macrolides, sulfonamides) were monitored, using a validated LC-MS/MS method, based on their number of registrations at the Ministry of Health. Ten antibiotics, ampicillin, cefuroxime, cefotaxime, clarithromycin, azithromycin, sulfamethoxazole, trimethoprim, ofloxacin, norfloxacin, and ciprofloxacin were detected in the samples at different concentrations. Notably, sulfonamides and quinolones were occasionally detected at very high concentration, such as sulfamethoxazole (252 μg/L), trimethoprim (107 μg/L), ofloxacin (85 μg/L), and ciprofloxacin (41 μg/L). In this study, concentration...Continue Reading

Citations

Aug 20, 2019·Water Environment Research : a Research Publication of the Water Environment Federation·Daniel D SnowJonathan Brett Sallach
Sep 11, 2019·Water Environment Research : a Research Publication of the Water Environment Federation·Archie NgLokesh P Padhye
Nov 22, 2019·Environmental Science and Pollution Research International·Saidy C Ayala-DuránRaquel F Pupo Nogueira
Sep 22, 2020·Critical Reviews in Microbiology·Syeda Fatima NadeemSalvatore Massa
May 27, 2020·Environmental Science and Pollution Research International·Thanh Huy NgoTrung Hai Huynh
Nov 27, 2018·Bioresource Technology·Thanh-Tin NguyenPhan-Thai-Vy Nguyen
Nov 22, 2019·European Journal of Pharmacology·Ewa FelisEwa Korzeniewska
Feb 13, 2021·Environmental Pollution·Rayane Kunert LangbehnHugo Moreira Soares
Feb 21, 2019·Journal of Environmental Management·Yujia XiangZhi Zhou
Mar 29, 2021·Journal of Environmental Management·K Nava-AndradeV Rodríguez-González
May 1, 2021·Environmental Science and Pollution Research International·Anita KotwaniDeeksha Kaloni
May 28, 2021·Archives of Environmental Contamination and Toxicology·Fanxing KongQiuya Zhang
May 16, 2021·Journal of Hazardous Materials·M MagureanuD Hong
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lucía Rodríguez-LópezManuel Arias-Estévez
Jul 26, 2019·The Science of the Total Environment·Ngoc Han TranKarina Yew-Hoong Gin
Jun 29, 2021·Canadian Journal of Public Health = Revue Canadienne De Santé Publique·Harold SchwartzConstantine Tikhonov
Jul 7, 2021·Expert Review of Anti-infective Therapy·Giorgia SulisSumanth Gandra
Feb 12, 2020·The Science of the Total Environment·Thomas Thiebault
May 22, 2020·Ecotoxicology and Environmental Safety·Zhen LiXiang Liu
Jan 15, 2022·Environmental Science and Pollution Research International·Anwar HossainHiroyuki Matsuda

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