Occurrence of fatigue over 20 years after recovery from Guillain-Barré syndrome

Journal of the Neurological Sciences
Vivian E DroryAmos D Korczyn

Abstract

Reports regarding outcome of Guillain-Barré syndrome (GBS) are usually limited to relatively short follow-up. We assessed the occurrence of fatigue and correlated it to clinical measures in patients who had suffered from GBS over 20 years previously. We contacted 24 patients with GBS requiring in-hospital rehabilitation during the years 1970-1987. Disability was established at rehabilitation admission using the Hughes scale (HS). Disability and fatigue were assessed at time of this study by the Overall Disability Sum Score (ODSS) and the Fatigue Severity Scale (FSS). Mean HS at admission was 2.5 ± 0.7, and at follow-up 1.1 ± 1.3. Mean ODSS was 2.8 ± 3.6, FSS was 4.4 ± 2. Ten patients reported severe fatigue (>5). Very good correlations were found between FSS and HS at admission and follow-up and between FSS and ODSS. FSS was not influenced by patients' age, age at disease onset, gender or time from GBS to the study. Fatigue can persist after apparent recovery from GBS and remain severe for many years.

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Citations

Dec 8, 2015·Expert Review of Clinical Immunology·Ying WangJie Zhu
Sep 14, 2013·Journal of the Peripheral Nervous System : JPNS·Antonios KerasnoudisMin-Suk Yoon
Jul 1, 2015·Current Pain and Headache Reports·Constantine FarmakidisSteven Herskovitz
Sep 10, 2014·Clinical Rehabilitation·Anette ForsbergGerd Ahlström
May 15, 2018·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Vesna MarticZorica Stevic
Nov 11, 2019·Acta Neurologica Scandinavica·Gordana DjordjevicStojan Peric
May 11, 2020·Muscle & Nerve·Andrew LawleyYusuf A Rajabally
Jul 28, 2020·Muscle & Nerve·Karissa L GableJeffrey A Allen
Dec 14, 2018·Therapeutic Advances in Neurological Disorders·Min-Suk YoonAnna Lena Fisse
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Dec 3, 2016·Physiotherapy Canada. Physiothérapie Canada·Nicholas Simatos ArsenaultAaron Sweeney
Nov 5, 2021·The Neurologist·Aleksandar StojanovStojan Peric

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