Occurrence of only myoclonic jerks in juvenile myoclonic epilepsy

Acta Neurologica Scandinavica
S JainM C Maheshwari

Abstract

The clinical data on individuals who were diagnosed to have juvenile myoclonic epilepsy (JME) on the basis of myoclonic jerks alone has been analysed. The points in favour and against individuals with only myoclonic jerks being classified as "affected" for research on JME are discussed. We studied 15 persons diagnosed with JME on the basis of only myoclonic jerks in a series of 161 patients with JME and their relatives. Detailed information on the seizure types in JME patients and their family members was collected. All affected individuals were examined by one person and had at least one conventional scalp EEG. CT/MRI of the brain was done as and when indicated. Nine of these were probands while 6 were the relatives of JME patients. The EEG was abnormal in 8 of 9 probands and 1 of 6 relatives with only myoclonic jerks. All the 9 probands and 2 relatives with only myoclonic jerks were treated with anti-epileptic drugs. Three of the 4 relatives had spontaneous remission of jerks after variable intervals. Four of 15 persons with only myoclonic jerks had a first degree relative with definite JME. It appears that persons with myoclonic jerks alone may represent a benign subgroup of JME that may be genetically distinct from classic ...Continue Reading

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Citations

Nov 14, 2000·Epilepsy Research·B ClemensZ Barta
Sep 12, 2003·Seizure : the Journal of the British Epilepsy Association·J VijaiK Radhakrishnan
Feb 24, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C Baise-ZungR M Grossmann
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Oct 6, 2011·Medicinski pregled·Ksenija BozićSlobodan Sekulić
May 8, 2015·Acta Neurologica Scandinavica·K M ParkS E Kim
May 6, 2014·Seizure : the Journal of the British Epilepsy Association·Sita JayalakshmiSurath Mohandas
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Mar 1, 2012·Epilepsy & Behavior : E&B·Pramod KrishnanParthasarathy Satishchandra
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Jun 14, 2013·Epilepsy & Behavior : E&B·Pierre GentonJavier Salas-Puig
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Jun 21, 2006·Expert Review of Neurotherapeutics·Alberto VerrottiEmilio Franzoni
Jul 9, 2014·Brain : a Journal of Neurology·Britta WandschneiderMatthias J Koepp
Apr 26, 2003·Acta Neurologica Scandinavica·S JainA Narula
Mar 3, 1998·Acta Neurologica Scandinavica·S JainM C Maheshwari
Sep 7, 2016·Acta Neurologica Scandinavica·B E SwartzM L Su
Mar 31, 2021·Brain & Development·Nicola PietrafusaNicola Specchio

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