Abstract
Outbreaks of acute encephalitis syndrome (AES) with high fatality and disability, are reported every year in the Gorakhpur region of Uttar Pradesh, India, with the etiology of >60% of the cases being attributed to scrub typhus. In the present study, the prevalence of Orientia tsutsugamushi, the etiological agent of scrub typhus, was investigated among animal hosts and their ectoparasitic trombiculid mites prevalent in AES-reported areas of Gorakhpur. A total of 154 rodents/shrews were collected using 777 Sherman traps set in 12 study villages, and the overall trap rate was 19.8%. In total, 2726 trombiculid mites belonging to 12 species were collected from 154 rodents/shrews trapped. The shrew mouse Suncus murinus was the predominant animal species (78.6%) collected. The principal vector mite Leptotrombidium deliense was the predominant species (82.7%), and its index was 14.6 per animal. Of 114 rodent/shrew sera samples screened through the Weil-Felix test, 57% were positive for antibodies against O. tsutsugamushi. Of 128 blood samples tested by polymerase chain reaction (PCR), one rodent sample was positive for the gene encoding 56 kDa protein and 25 for 60 kDa. Among 2726 mite samples tested as 315 pools through nested PCR, se...Continue Reading
References
May 25, 1999·Microbiology and Immunology·J S Kang, W H Chang
Sep 1, 1999·Journal of Medical Entomology·S P FrancesP Tanskul
May 23, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Daryl J KellyGregory A Dasch
Jul 5, 2003·Journal of Clinical Microbiology·Jung-Hee LeeSeung-Hyun Lee
Mar 22, 2007·Human Vaccines·Suchismita Chattopadhyay, Allen L Richards
Feb 28, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Daryl J KellyAllen L Richards
May 7, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D H ParisN P J Day
Mar 30, 2011·Vector Borne and Zoonotic Diseases·Hee Il LeeE-Hyun Shin
Jul 1, 2011·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Jani BorahJagadish Mahanta
May 9, 2012·Annals of Indian Academy of Neurology·K SaifudheenV Abdul Gafoor
Jan 8, 2013·Indian Journal of Community Medicine : Official Publication of Indian Association of Preventive & Social Medicine·Nagabhushana Rao Potharaju
May 8, 2013·Emerging Infectious Diseases·Wuttikon RodkvamtookNarongrid Sirisopana
Mar 25, 2014·The Journal of Infection·Prashant RanjanManoj Murhekar
Aug 20, 2014·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Mathew GriffithOoriapadickal Cherian Abraham
Dec 23, 2014·Emerging Infectious Diseases·George M VargheseO C Abraham
Sep 7, 2016·The Journal of Infection·Manoj V MurhekarMohan Gupte
May 6, 2017·The Indian Journal of Medical Research·Sadanandane CandasamyJambulingam Purushothaman
Citations
Oct 23, 2020·PLoS Neglected Tropical Diseases·James FisherLynn Soong
Feb 20, 2021·BMC Infectious Diseases·Meghnath DhimalKhem B Karki
May 17, 2019·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Abhay KumarAshish Bhalla
Jul 1, 2021·Vector Borne and Zoonotic Diseases·Sthita Pragnya BeheraVijay P Bondre
Jul 31, 2021·Experimental & Applied Acarology·Candasamy SadanandanePurushothaman Jambulingam
Dec 2, 2021·Journal of Medical Entomology·John Antony Jude PrakashK C Seran
Apr 29, 2021·The Indian Journal of Medical Research·Manoj V MurhekarMohan D Gupte