Occurrence of pneumococci with resistance or decreased susceptibility to penicillin in southeast Sweden

Scandinavian Journal of Infectious Diseases
E Kihlström, B Normann

Abstract

The minimal inhibitory concentrations (MICs) of 14 beta-lactam and non-beta-lactam antibiotics were determined for all pneumococci with intermediate susceptibility (I), (n = 26) or resistance (R), (n = 15) to penicillin G isolated at the Clinical Microbiology Laboratory, University Hospital, Linköping, Sweden during 1994. These isolates accounted for 3% of all pneumococcal isolates. The results were compared with those of 26 penicillin-susceptible isolates. The MICs of all tested beta-lactam antibiotics increased with MICs of penicillin G. The least increase and the lowest MICs of these agents were recorded for cefotaxime and imipenem. 27% of I- and R-strains were multiple-resistant, most often to tetracycline, trimethoprim-sulfametoxazole, erythromycin, chloramphenicol and clindamycin. All strains were susceptible to vancomycin and rifampicin. I-strains belonged to at least 5 different serotypes. However, 12 of the 15 R-strains were serotype 9 and 6 of these were recovered during contact tracing, indicating spread of a single clone within day-care centres.

References

Jun 27, 1992·Lancet·K G KristinssonO Steingrímsson
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M R Jacobs
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P C Appelbaum
Jan 1, 1991·The Journal of Hospital Infection·K D Allen
Apr 1, 1990·Clinical Microbiology Reviews·K P Klugman
May 1, 1988·The American Journal of Medicine·P F ViladrichR Pallares
Sep 1, 1965·The American Journal of the Medical Sciences·J W KislakM Finland
Oct 1, 1994·Journal of Clinical Microbiology·L P JettéP Turgeon
Jun 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G A Jacoby
Mar 1, 1994·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·A Forsgren, M Walder

❮ Previous
Next ❯

Citations

Jul 2, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L SombreroUNKNOWN ARIVAC consortium
Aug 18, 1999·The American Journal of Medicine·A Ortqvist
Jan 6, 2001·The Pediatric Infectious Disease Journal·E MelanderS Mölstad
May 7, 1999·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·M K LalithaG Kronvall
Mar 1, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Karl Ekdahl, Otto Cars
Feb 24, 2001·Acta Paediatrica. Supplement·M ErikssonK Ekdahl

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.