Occurrence of prochymosin variants in the abomasum of bovine foetuses and calves

Zentralblatt für Veterinärmedizin. Reihe A
M Wiśliński, M Popielarz


Prochymosin variants were analysed in single abomasa from 67 foetuses (3-9 months of gestation) and 33 calves (about 6 weeks old) of Black-and-White cattle collected in a slaughter house. The method of agarose gel electrophoresis followed by detection of proteolytic activity was used. Three distinct prochymosins A, B and C that occurred singly or in pairs (with equal proteolytic activities of both components) were found. Chymosin A, B and C obtained after conversion of corresponding prochymosins, demonstrated similar electrophoretical mobilities like the three chymosin fractions contained in commercial rennin (Sigma, USA). Our chymosin B showed identical mobility as the amidated form of recombined chymosin B contained in Chymogen (Chr. Hansen's Lab., Denmark A/S). Prochymosin A, B and C in the examined animals were precursors of corresponding chymosins and were controlled by three separate codominant alleles. The following prochymosin phenotypes were found: AA (30), AB (32), AC (4), BB (29), BC (4) and CC (1). Chi-square analysis demonstrated significant differences between the observed and expected numbers of phenotypes. The gene frequencies of prochymosin A, B and C were 0.48, 0.47 and 0.05, respectively.


Nov 1, 1977·The Biochemical Journal·N Asato, A G Rand
Mar 1, 1979·European Journal of Biochemistry·V B PedersenB Foltmann
Sep 1, 1991·Journal of Biotechnology·M KolmerI Ulmanen
Jan 1, 1992·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·A Andrén
Jan 1, 1992·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·B Foltmann
Nov 1, 1986·The Journal of Dairy Research·W J DonnellyD Walls
Jan 1, 1987·Animal Genetics·B SeibertB Senft
Oct 1, 1973·The American Journal of Digestive Diseases·J C ManglaM D Turner
Feb 1, 1974·The Journal of Dairy Research·P GarnotB Ribadeau-Dumas
Oct 1, 1972·The Biochemical Journal·N Asato, A G Rand
Nov 1, 1971·Analytical Biochemistry·N Asato, A G Rand
Feb 1, 1971·The Journal of Dairy Research·A V Castle, J V Wheelock
Apr 10, 1982·Nucleic Acids Research·T J HarrisM T Doel
Jun 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·J S EmtageP A Lowe


Aug 1, 1995·Zentralblatt für Veterinärmedizin. Reihe A·M WiślińskiR Bobowiec
Jan 29, 2009·The Veterinary Clinics of North America. Food Animal Practice·Tessa S Marshall

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