Abstract
To describe the occurrence of serious bacterial infections (SBIs) in well-appearing, afebrile infants aged 60 days or younger with an apparent life-threatening event (ALTE). We retrospectively reviewed microbiologic testing in a cohort of well-appearing, afebrile infants aged 60 days or younger who presented with an ALTE to a children's hospital emergency department between January 2002 and July 2005. All patients were admitted and followed up for 6 months. Comparisons were made among those who did and did not undergo microbiologic testing and full sepsis evaluation (blood, urine, and cerebrospinal fluid) and those who did and did not have an SBI. Of 182 patients, 112 (61.5%) underwent microbiologic testing, and 53 (29.1%) had a full sepsis evaluation. Five patients (2.7%; 95% confidence interval, 0.9%-6.3%) had an SBI including 3 positive results in blood cultures, 1 positive result in urine culture, and 1 positive result for pertussis by polymerase chain reaction. No patient had a positive result in cerebrospinal fluid culture (95% confidence interval, 0%-5.7%). Patients with a history of prematurity were more likely to have an SBI (6.7% vs. 0.8%, P = 0.04). Serious bacterial infection occurred in 2.7% of well-appearing, afeb...Continue Reading
References
May 1, 1984·American Journal of Diseases of Children·R Dagan, R Gorodischer
Jul 2, 1999·Pediatric Emergency Care·C GrayE Molyneux
Oct 3, 2001·Pediatrics·S M HerrS S Choi
Jan 5, 2002·Emergency Medicine Journal : EMJ·F Davies, R Gupta
Sep 3, 2002·Pediatrics·Raymond D PitettiMary Clyde Pierce
Oct 3, 2003·Pediatrics International : Official Journal of the Japan Pediatric Society·Kazuko OkadaMakiko Osawa
Dec 4, 2003·European Journal of Pediatrics·André Kahn, UNKNOWN European Society for the Study and Prevention of Infant Death
Mar 11, 2004·The American Journal of Emergency Medicine·Andrew D De PieroJames M Chamberlain
May 1, 2004·Clinical Pediatrics·Karen S EdwardsDonald A Brand
Oct 23, 2004·Archives of Disease in Childhood·M C McGovern, M B H Smith
Apr 5, 2005·Pediatrics·Donald A BrandKaren S Edwards
Jul 13, 2005·Pediatric Clinics of North America·Craig C Dewolfe
Oct 6, 2005·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Raymond D PitettiRobert Hickey
Apr 4, 2007·Pediatrics·Ilene Claudius, Thomas Keens
Citations
Feb 19, 2013·The Journal of Pediatrics·Joel S TiederMichael B H Smith
Jul 14, 2012·Advances in Pediatrics·Carol D Berkowitz
Apr 5, 2011·Paediatric Respiratory Reviews·Naif Al Khushi, Aurore Côté
Feb 4, 2014·The Journal of Pediatrics·Ilene ClaudiusGenevieve Santillanes
Sep 29, 2015·Pediatric Emergency Care·Aaron S MillerRana E El Feghaly
Jul 24, 2020·Curēus·Ali A Alhaboob
Jul 7, 2020·Frontiers in Physiology·Stéphanie NaultJean-Paul Praud
Jul 31, 2009·Journal of Proteome Research·Hui LiXuan-Xian Peng