PMID: 8997435Dec 1, 1996Paper

Occurrence of the Carabelli trait in twins discordant or concordant for cleft lip and/or palate

Acta Odontologica Scandinavica
T Laatikainen, R Ranta

Abstract

The frequency and expression of the Carabelli trait among 36 twin pairs discordant or concordant for cleft lip and/or palate were investigated. Four of 10 monozygotic (MZ) and 24 of 26 dizygotic (DZ) pairs of twins were discordant for clefts. The frequency of the trait on the first upper molars of the noncleft subjects was 79%. It varied from 54% to 61% in the subjects with clefts, and the frequency of the trait decreased with increasing extension of the cleft. The occurrence of the trait was bilateral in more than 90% of the MZ and the DZ subjects. MZ twins had a higher concordance rate for the corresponding molar comparisons and for cross-twin comparisons than did the DZ pairs. The corresponding polychoric correlations for MZ twin pairs were estimated to be 1.0, and for the DZ twin pairs estimates ranged from 0.4 to 0.5. Thus, genetic factors appear to control the Carabelli trait, and the heritability seems to be high even in our cleft lip and/or palate twins.

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Citations

Jul 29, 2018·American Journal of Physical Anthropology·Christopher M StojanowskiDebbie Guatelli-Steinberg
Feb 13, 2019·American Journal of Physical Anthropology·Christopher M StojanowskiDebbie Guatelli-Steinberg
Feb 20, 2020·American Journal of Physical Anthropology·Kathleen S PaulGrant C Townsend
Jun 20, 2020·European Journal of Orthodontics·Wael AwadhDavid P Rice
Jan 25, 2022·Annals of Human Biology·Bhavyaa RSneha S Patil

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