Octamer-binding proteins in diverse hemopoietic cells.

Molecular and Cellular Biology
P N Cockerill, S P Klinken

Abstract

The immunoglobulin genes have B-cell-specific promoter and enhancer elements. The regulation of these elements is thought to be mediated to a large degree by the trans-activating factor oct-2, which binds the octamer element (ATTTGCAT). We have further examined the role of this octamer element in directing the lymphoid-specific expression of the immunoglobulin H enhancer. No direct relationship was found between the levels of expression of the Cmu gene and oct-2. Indeed, variable amounts of oct-2 were detected in all of the hemopoietic lineage cells tested in this study.

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Citations

Apr 2, 2014·Frontiers in Immunology·Lynn CorcoranStephane Chevrier
Jun 28, 1996·The Journal of Biological Chemistry·H ChenD G Tenen
Dec 10, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mabel Salas, Laurel A Eckhardt
Feb 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Lynn M CorcoranPatrick O Humbert
Nov 9, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·A G BertP N Cockerill
Nov 1, 1995·Brain Research. Molecular Brain Research·N N NinkinaJ N Wood
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Apr 29, 1993·Biochimica Et Biophysica Acta·C P Verrijzer, P C Van der Vliet
Jul 15, 1992·Biochemical and Biophysical Research Communications·P W Tebbey, T M Buttke

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