Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles

Chemico-biological Interactions
F KösslerG Küchler

Abstract

Octanol (1 mM) or octanoate (10 mM) almost totally depress the contraction amplitude of directly stimulated muscles in a few minutes. Octanoate in a concentration of 2 mM/l decreases the contraction amplitude by 20% and retards the caffeine contracture. The ratio between twitch and tetanus is affected by octanol only. The results suggest that octanol and octanoate alter binding or releasing properties for Ca2+ of skeletal muscle cells.

References

Oct 6, 1975·Biochimica Et Biophysica Acta·A BruniJ de Gier
Jan 1, 1978·The Journal of Physiology·P W GageD Van Helden
Feb 19, 1976·Biochimica Et Biophysica Acta·K Inoue, T Kitagawa
Sep 13, 1976·Biochimica Et Biophysica Acta·A SandowE C Sphicas
Feb 1, 1975·Journal of Molecular and Cellular Cardiology·E Wasilewska-Dziubińska
Feb 1, 1975·Journal of Molecular and Cellular Cardiology·L H Opie, W F Lubbe
Jan 1, 1975·The Journal of Membrane Biology·J Z YehT Narahashi
Feb 1, 1976·Canadian Journal of Physiology and Pharmacology·S H Roth, L Spero
Jul 6, 1973·Biochimica Et Biophysica Acta·M Kondo, M Kasai
Feb 1, 1974·Journal of Theoretical Biology·D Papahadjopoulos
Mar 15, 1974·Experientia·J BorbolaL Szekeres
Jul 12, 1974·Biochimica Et Biophysica Acta·M Grunze, B Deuticke
Nov 1, 1964·The Journal of General Physiology·J W MOOREM TAKATA

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