Ocular adnexal lymphoma and Helicobacter pylori gastric infection

American Journal of Hematology
Didier DecaudinMarc Lecuit

Abstract

There is a causal association between Helicobacter pylori (Hp) gastric infection and the development of gastric MALT lymphoma. In contrast, the link between Hp gastric infection and the development of extragastric lymphoma has not been thoroughly investigated. We, therefore, studied the prevalence of gastric Hp infection at initial diagnosis of ophthalmologic and nonophthalmologic extragastric lymphoma patients. Three cohorts of patients were studied: a first one of 83 patients with OAL, a second one of 101 patients with extraophthalmologic extragastric lymphoma, and a third one of 156 control individuals (control) without malignant lymphoma. Gastric Hp infection was investigated by histopathological analysis and Hp-specific PCR assay on gastric biopsy tissue samples. We found gastric Hp infection in 37 OAL patients (45%), in 25 extraophthalmologic extragastric lymphoma cases (25%), and in 18 controls individuals (12%) (P < 0.0001 OAL/C and P < 0.01 OAL/extra-OAL cases). Gastritis was found in 51% and 9% of Hp-positive and Hp-negative lymphoma patients, respectively (P < 10(-4)). Gastric Hp infection only correlated with MALT/LPL lymphoma (P = 0.03). There is a significant association between gastric Hp infection and MALT/LPL O...Continue Reading

References

Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Sep 30, 1993·The New England Journal of Medicine·UNKNOWN International Non-Hodgkin's Lymphoma Prognostic Factors Project
May 5, 1994·The New England Journal of Medicine·J ParsonnetG D Friedman
Nov 30, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N L HarrisC D Bloomfield
Nov 29, 2002·Blood·Emanuele ZuccaUNKNOWN International Extranodal Lymphoma Study Group
Jan 16, 2004·The New England Journal of Medicine·Marc LecuitOlivier Lortholary
Apr 22, 2004·Journal of the National Cancer Institute·Andrés J M FerreriRiccardo Dolcetti
Aug 10, 2005·American Journal of Ophthalmology·Katherine M FalkenhagenJustine R Smith
Sep 13, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Pedro Farinha, Randy D Gascoyne
Jan 25, 2006·Investigative Ophthalmology & Visual Science·Sergio Claudio SaccàAlfredo Rebora
Feb 21, 2006·The British Journal of Ophthalmology·P S TsaiD A Sullivan
Mar 2, 2006·Journal of the National Cancer Institute·Patricia de CremouxDidier Decaudin
Mar 22, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Birgit GrünbergerMarkus Raderer
Apr 28, 2006·Blood·Didier DecaudinLivia Lumbroso-Le Rouic
Jun 14, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Markus RadererAndreas Chott
Jun 27, 2006·Scandinavian Journal of Infectious Diseases·Mårten Kivi, Ylva Tindberg
Mar 27, 2007·Best Practice & Research. Clinical Gastroenterology·Hoda M Malaty
Oct 11, 2007·Helicobacter·Philippe Lehours, Ozlem Yilmaz
Mar 29, 2008·The British Journal of Ophthalmology·Sung-Bok LeeChang-Sik Kim

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Citations

Apr 30, 2013·Journal of Cancer Research and Clinical Oncology·Gustavo SavinoMaria Antonietta Blasi
Apr 24, 2012·American Journal of Clinical Pathology·Jason R KaramchandaniYasodha Natkunam
Aug 9, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F Suarez, M Lecuit
Aug 6, 2013·Veterinary Ophthalmology·Christina McCowanRobin Stanley
Oct 4, 2014·World Journal of Gastroenterology : WJG·Traci L Testerman, James Morris
May 25, 2016·Cancer Control : Journal of the Moffitt Cancer Center·Jean Guffey JohnsonReza Setoodeh
Jun 20, 2020·Pathology Oncology Research : POR·Antonio TravaglinoMassimo Mascolo
Feb 24, 2020·Pathology, Research and Practice·Antonio TravaglinoMassimo Mascolo
Sep 16, 2020·Ophthalmic Plastic and Reconstructive Surgery·Evan Kalin-HajduIsabelle Hardy

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