Ocular allergy and dry eye syndrome

Current Opinion in Allergy and Clinical Immunology
L Bielory

Abstract

Ocular allergy is a common clinical disorder that includes dry eye syndrome in its differential diagnosis. While ocular allergy treatments have continued to evolve since the early 1990s when the new prescription topical agents became available, there have been no major advances in the treatment of dry eye syndrome other than changes in the chemical structures of various artificial tear formulations. This review is timely and relevant due to the recent FDA approval of several new agents for the treatment of dry eye syndrome. The literature reviewed brings the practicing allergist/clinical immunologist up to date on the recent understanding that T-cell activation plays a key role in dry eye syndrome immunopathophysiology. In addition, the parallel novel treatment developments are discussed, including new formulations for tear substitutes, topical cyclosporine A and purinergic receptor (P2Y2) agonists. The recent developments bode well for patients who are referred for ocular allergy, including dry eye syndrome. A new formulation for a tear substitute that generates a 'soft gel' covering the ocular surface (in situ) is ideal for early forms of dry syndrome, while topical cyclosporine is the first new real prescription treatment fo...Continue Reading

References

Jan 1, 1994·Advances in Experimental Medicine and Biology·C ChaumeilO Kogbe
Jan 14, 1999·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·P VersuraR Caramazza
Sep 30, 2000·Advances in Therapy·J D NelsonJ D Hirsch
Nov 1, 2000·Acta Ophthalmologica Scandinavica. Supplement·G J Berdy, B Hedqvist
Aug 13, 2002·International Archives of Occupational and Environmental Health·T LindgrenD Norbäck
Jan 9, 2003·The American Journal of Medicine·Leonard Bielory
Jul 31, 2003·American Journal of Ophthalmology·Debra A SchaumbergM Reza Dana
Nov 7, 2003·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·F LallemandR Gurny
Nov 26, 2003·Japanese Journal of Ophthalmology·Asako MoriKazuo Tsubota
Dec 19, 2003·Expert Opinion on Investigational Drugs·Kelly K NicholsDonald J Kellerman
Jan 6, 2004·Current Eye Research·Mike T ChristensenJerry M Stein
Mar 10, 2004·Archives of Ophthalmology·Scot E MossBarbara E K Klein

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Citations

Oct 16, 2012·Current Allergy and Asthma Reports·Leonard BieloryRobert Goldberg
Feb 20, 2007·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Leonard Bielory
Mar 19, 2013·Italian Journal of Pediatrics·Mario La RosaAlfredo Reibaldi
Aug 28, 2009·Expert Opinion on Emerging Drugs·Catherine Origlieri, Leonard Bielory
Mar 1, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Milton M HomLeonard Bielory
Jul 31, 2010·Immunology and Allergy Clinics of North America·Brett Bielory, Leonard Bielory
Oct 27, 2015·Medicine·Edoardo VillaniPaolo Nucci
Feb 20, 2008·Immunology and Allergy Clinics of North America·Leonard Bielory
Feb 20, 2008·Immunology and Allergy Clinics of North America·Michael A Lemp, Leonard Bielory
Nov 29, 2005·The Medical Clinics of North America·Leonard Bielory
Sep 14, 2011·The Mount Sinai Journal of Medicine, New York·Leonard Bielory
Apr 1, 2014·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Leonard Bielory
Jun 25, 2013·Jornal de pediatria·Leonard Bielory
Aug 16, 2013·Current Opinion in Allergy and Clinical Immunology·Leonard Bielory, Basharut A Syed
Aug 8, 2014·Current Opinion in Allergy and Clinical Immunology·Basharut A SyedLeonard Bielory
Sep 7, 2006·Current Opinion in Allergy and Clinical Immunology·Leonard Bielory
Sep 1, 2005·Current Opinion in Allergy and Clinical Immunology·Michael E SternJerry Y Niederkorn
Sep 1, 2005·Current Opinion in Allergy and Clinical Immunology·Alessandra MiceraAlessandro Lambiase
Jun 23, 2020·Journal of Ophthalmology·Xiang-Tian MengHong-Yan Zhou
Feb 25, 2021·Photobiomodulation, Photomedicine, and Laser Surgery·Dan LiBiao Cheng

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