Ocular basal cell carcinoma: a brief literature review of clinical diagnosis and treatment

OncoTargets and Therapy
Yingyun ShiXianqun Fan

Abstract

Basal cell carcinoma (BCC) is a common malignant tumor throughout the world. One of the known risk factors of BCC is intense exposure to ultraviolet radiation. More than 50% of BCCs of the eyelid initially occur on the lower lid. The gold standard of diagnosis of BCC is histopathology. Treatment options for BCC consist of surgery, vismodegib, radiotherapy and imiquimod. Surgical excision using Mohs micrographic surgery or wide surgical excision with frozen section margin control is the first consideration for treatment of periocular BCC. Eyelid reconstruction should be carefully considered as both function and esthetic outcome in patients are important after clear excision of tumors. Exenteration is considered in the case of extensive orbital invasion or high-risk aggressive tumors in order to reduce the rate of recurrence.

Citations

Jun 6, 2018·BMJ Case Reports·Supriya Jayant KhardenavisAnirudda Deshpande
Oct 3, 2019·The Journal of Craniofacial Surgery·Doruk OrgunHiroshi Mizuno
Dec 25, 2019·Technology in Cancer Research & Treatment·Zhe QuanNingjing Song
Dec 7, 2019·Ophthalmic Plastic and Reconstructive Surgery·Lauren R SchafferHans E Grossniklaus
May 13, 2020·Oncology Reviews·Alena FurdovaJuraj Sekac
Oct 29, 2017·Acta neurochirurgica·Satoshi SuzukiTakuya Inoue
Apr 20, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Nataša MihailovicNicole Eter
Jul 31, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Alexander C RokohlLudwig M Heindl
Jul 10, 2019·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Ketty PerisUNKNOWN European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Rese
Jul 17, 2019·Journal of the American Academy of Dermatology·Ashley WysongIren Kossintseva
Jan 23, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Laurel L WessmanIan A Maher

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Methods Mentioned

BETA
confocal microscopy
imaging technique

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