Ocular blood flow in experimental glaucoma: a study in cynomolgus monkeys

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
A AlmC Percicot

Abstract

Experimental glaucoma was induced in 1 eye of 6 cynomolgus monkeys by laser treatment of the trabecular meshwork. In 5 of the 6 monkeys the increased intraocular pressure (IOP) caused marked glaucomatous damage in the experimental eye. Ocular blood flow was determined with labeled microspheres 4 years after the laser treatment. IOP was regulated with an external reservoir. With the same perfusion pressure in both eyes no statistically significant difference was observed between the 2 eyes for total ocular blood flow or for blood flow through any of the ocular tissues. Total ocular blood flow was 343.5 +/- 61.4 mg/min (mean +/- SEM) in the control eye and 385.3 +/- 107.7 mg/min in the experimental eye.

Citations

Jun 6, 2013·Investigative Ophthalmology & Visual Science·Grant CullLin Wang
Jul 2, 2005·Journal of Glaucoma·Carol A Rasmussen, Paul L Kaufman
Nov 9, 2005·Journal of Glaucoma·William W DawsonChristine L Percicot

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