PMID: 9536883Apr 16, 1998Paper

Ocular changes associated with Giardia lamblia infection in children

The British Journal of Ophthalmology
A CorsiF M Paone

Abstract

The protozoan disease giardiasis can cause ocular complications, including "salt and pepper" retinal changes. Ophthalmic examinations were performed in 141 children (mean age 4.7 (SD 2.0) years) with active or past giardiasis diagnosed on the basis of microscopic examination of stool specimens or duodenal secretions--53 were newly diagnosed and untreated (group A), 50 had active infections in spite of metronidazole therapy (group B), and 38 had been successfully treated, with negative stool specimens for 1-3 years (group C). 300 children with no evidence of giardiasis were used as controls. Salt and pepper retinal changes (with normal electroretinographic findings) were diagnosed in 28 (19.9%) of the patients with giardiasis (11 from group A, 10 from group B, and seven from group C), including five pairs of siblings. In all subgroups, the children with retinal changes were consistently younger than those with normal retinas. In eight cases, the lesions could be visualised only with direct ophthalmoscopy. Our findings indicate that asymptomatic, non-progressive retinal lesions are particularly common in younger children with giardiasis. This risk does not seem to be related to the severity of the infection, its duration, or the ...Continue Reading

References

Aug 1, 1990·Journal of Pediatric Gastroenterology and Nutrition·M Pettoello MantovaniS Guandalini
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Citations

Jun 27, 2007·Parasitology Research·Annunziata GiangasperoOlga Brandonisio
Oct 12, 2000·Clinical Microbiology Reviews·S A KlotzS I Butrus
Oct 2, 2012·Interdisciplinary Perspectives on Infectious Diseases·Amal R NimirIbrahim Abdel Aziz Ibrahim
Jan 1, 2014·World Journal of Gastroenterology : WJG·Marie C M Halliez, André G Buret
Feb 18, 2016·Journal of Helminthology·H I H IsmailA L Ali
Feb 11, 2016·Indian Journal of Ophthalmology·Nagwa Mostafa El-Sayed, Elmeya Hassan Safar
Jun 21, 2011·International Journal for Parasitology·James A CottonAndre G Buret
Apr 10, 2007·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Frances M KearneyGlen A Gole
Oct 22, 2011·The American Journal of Medicine·Paul T CanteyMichael J Beach
Dec 14, 2016·Indian Journal of Ophthalmology·Dipankar DasApurba Deka
Aug 1, 2014·Retina·Rupesh AgrawalCarol L Shields
Sep 19, 2018·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Syed Shoeb Ahmad

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