Ocular manifestations of acquired immunodeficiency syndrome in Korea.

Journal of Korean Medical Science
Sang Jin KimMyoung-don Oh

Abstract

The clinical features of HIV/AIDS-related ocular manifestations in Korean patients were investigated in this study. Data on 200 consecutive Korean patients diagnosed with AIDS who visited the Seoul National University Hospital from January 2003 to June 2008 were reviewed. Fifty-seven patients (28.5%) had ocular manifestations, and they showed significantly lower CD4+ T cell count than patients without ocular manifestations. Among them, 23 (40.3%) patients showed retinal microvasculopathy, and 22 (38.5%) patients showed cytomegalovirus (CMV) retinitis. Other manifestations included retinal vein occlusion (n = 4), herpes zoster ophthalmicus (n = 4), syphilitic uveitis (n = 2), acute retinal necrosis (n = 1), and progressive outer retinal necrosis (n = 1). The mean CD4+ lymphocyte counts of the patients with retinal microvasculopathy and cytomegalovirus retinitis were 108.5 cells/µL and 69.4 cells/µL, respectively. In conclusion, ocular manifestations including CMV retinitis are common complications in Korean patients with AIDS even in the era of highly active anti-retroviral therapy. Compared to previous reports in western countries, prevalence of CMV retinitis is relatively low and CD4+ lymphocytes count at the time of diagnosis...Continue Reading

References

Jul 1, 1989·Ophthalmology·D A JabsJ G Bartlett
Aug 1, 1983·Ophthalmology·G N HollandR Y Foos
Feb 1, 1984·American Journal of Ophthalmology·W R FreemanM L Tapper
Nov 1, 1996·The Medical Clinics of North America·M L Tay-Kearney, D A Jabs
Oct 24, 1997·Archives of Ophthalmology·S Lewallen, P Courtright
Aug 8, 1998·The New England Journal of Medicine·S H MichaelsP Kissinger
Jan 14, 2003·Archives of Ophthalmology·Janet T HolbrookUNKNOWN Studies of Ocular Complications of AIDS (SOCA) Research Group
Mar 5, 2004·Survey of Ophthalmology·Tamara R Vrabec
Jul 17, 2004·Korean Journal of Ophthalmology : KJO·Se Joon WooHum Chung
Jun 4, 2005·Clinical & Experimental Ophthalmology·Weng T Ng, Patrick Versace
Aug 4, 2005·Retina·Daniel E GoldbergWilliam R Freeman
Jan 30, 2007·Ophthalmology·Douglas A JabsUNKNOWN Studies of the Ocular Complications of AIDS Research Group
Dec 25, 2007·American Journal of Ophthalmology·Gary N HollandUNKNOWN UCLA CMV Retinitis Study Group
Feb 20, 2008·American Journal of Ophthalmology·Gary N Holland
Jun 24, 2008·Survey of Ophthalmology·Varun VermaChi-Chao Chan

❮ Previous
Next ❯

Citations

Mar 14, 2013·Ocular Immunology and Inflammation·Sung Wook Park, Hyeong Gon Yu
Sep 7, 2018·Ocular Immunology and Inflammation·Chui-Lien TsenShwu-Jiuan Sheu
Aug 5, 2015·Korean Journal of Ophthalmology : KJO·Young Shin KimSung Jin Lee
May 13, 2020·Ocular Immunology and Inflammation·Remco P H PetersJohn H Kempen
Mar 17, 2017·BMC Infectious Diseases·Liang-Kung ChenChang Won Won
Apr 8, 2021·Southern African Journal of HIV Medicine·Dorsaf SaadouliHanene Tiouri

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.