Ocular manifestations of Alport syndrome.

International Journal of Ophthalmology
Jian-Min XuLing Wang

Abstract

To analyze the clinical manifestation of Alport syndrome, especially the ocular features. The physical, ophthalmologic and audiologic examination results of thirty-two patients with Alport syndrome were analyzed retrospectively. Thirty (93.7%) patients had some family history. All patients had renal disease: eighteen (56.3%) patients with chronic renal failure, four (12.5%) patients with renal insufficiency, and the other ten (31.3%) patients with hematuria. Twenty (62.5%) patients had sensorineural deafness. Thirteen (40.6%) patients had ocular deformity, five (15.7%) patients had typical ocular changes: three patients with anterior lenticonus, and two patients with macular flecks. Ocular anomalies are not requisite for the diagnosis of Alport syndrome. But its typical ocular features should be recognized by the ophthalmologists which supports the diagnosis.

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Related Papers

Zhonghua er ke za zhi. Chinese journal of pediatrics
Xu HeRong Chen
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Chun-Hua ZhuWei-Zhen Zhang
Nepalese Journal of Ophthalmology : a Biannual Peer-reviewed Academic Journal of the Nepal Ophthalmic Society : NEPJOPH
Charu JainKirti Jain
Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
Yanyan WangJudy Savige
© 2021 Meta ULC. All rights reserved