PMID: 12766033May 27, 2003

Ocular measurements throughout the adult life span of rhesus monkeys

Investigative Ophthalmology & Visual Science
Alcides FernandesJames G Herndon

Abstract

To examine the relationship of ocular components to refraction throughout the adult life span of the rhesus monkey (Macaca mulatta). Cycloplegic retinoscopy, A-scan ultrasonography, slit lamp examination, indirect ophthalmoscopy, and keratometry were performed in a cross-sectional study of 111 monkeys, aged 5 to 31 years. Lens thickness and anterior and vitreous chamber depths were measured from the echograms. The intercorrelations of these variables were analyzed, as well as their association with age and sex. In monkeys aged 5 to 15 years, the mean refractive value of +1.5 D with an SD of 1.7 D was maintained near the previously established developmental asymptote of +2 D. In monkeys older than 15 years, there was greater interindividual variation (SD = 4.5 D), including extreme myopia and hyperopia. The cornea became steeper with age. The axial length of the eyes increased up to 12 years of age and began to shorten after 20 years. Changes also occurred in the other individual components that constitute eye length. These age-related changes were decreased vitreous chamber depth, decreased anterior chamber depth, and increased lens thickness. In general, males had longer eyes than females. The eyes of old monkeys were more lik...Continue Reading

Citations

Jan 15, 2008·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·W WangA H Barber
Jun 12, 2009·Cutaneous and Ocular Toxicology·Chris J SompsGareth Phillips
Jul 24, 2012·Experimental Eye Research·Robert C AugusteynJean-Marie Parel
Feb 15, 2011·Experimental Eye Research·Elizabeth J ElsmoGillian J McLellan
Sep 29, 2007·Ophthalmology·Naoko KatoKazuo Tsubota
Jan 6, 2007·Veterinary Ophthalmology·N TuntivanichJanice Q Forcier
Dec 3, 2008·Veterinary Ophthalmology·Fabiano Montiani-FerreiraRogério R Lange
Apr 21, 2009·Brain Research·Yun YangYifeng Zhou
Nov 8, 2011·Biochimica Et Biophysica Acta·Peizhong MaoP Hemachandra Reddy
May 26, 2006·Vision Research·Xiangtian ZhouFan Lu
Nov 22, 2008·Journal of Biomedical Optics·Rebecca L VinceletteDavid J Lund
Jul 15, 2020·Investigative Ophthalmology & Visual Science·Tu M TranGlenn Yiu
Jun 15, 2019·Visual Neuroscience·William H RidderJames Burke

Related Concepts

Senility
Anterior Chamber of Eye Structure
Cornea
Prevalence Studies
Eye
Lens, Crystalline
Macaca mulatta
Ophthalmoscopy
Ocular Refraction
Vitreous Body Structure

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