Ocular morbidity in very low birth-weight infants with intraventricular hemorrhage

American Journal of Ophthalmology
J PhillipsR S Kirby

Abstract

To document ocular outcomes and prevalence of ocular disease in very low birth-weight infants with intraventricular hemorrhage. We retrospectively reviewed the records of all surviving very low birth-weight infants (1,500 g or less) admitted to the neonatal intensive care unit of our institution during 1992 and 1993. Of 252 survivors, 74 had complete ophthalmologic examinations at a mean adjusted age of 11 months. Of these 74 infants, 38 had intraventricular hemorrhage. Chi-square and multivariate analysis were used for statistical testing, in controlling for race, sex, and birth weight, and for other disease processes associated with prematurity. Of 38 infants with intraventricular hemorrhage, strabismus occurred in 14 (37%), esotropia in 12 (32%), and exotropia in two (5%). Of the 20 infants with grades III and IV intraventricular hemorrhage, 11 (55%) had esotropia; none had exotropia. Infants with grades III and IV intraventricular hemorrhage were at significantly greater risk for the development of esotropia than were infants with less severe or no hemorrhage (odds ratio, 5.0; P = .04). Mean adjusted age at diagnosis of strabismus was 8.5 months. Infants with periventricular leukomalacia (odds ratio, 6.3; P = .036) and neon...Continue Reading

Citations

May 29, 2002·Eye·S Mukherji, S E P Burgess
Nov 28, 2002·Mental Retardation and Developmental Disabilities Research Reviews·Michael X Repka
Sep 10, 2015·Journal of Child Neurology·Deborah K VanderVeenUNKNOWN ELGAN Study Investigators
Feb 1, 2008·Documenta Ophthalmologica. Advances in Ophthalmology·Miroslav KubaZuzana Kubová

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