Ocular myasthenia in sisters (author's transl)

Klinische Monatsblätter für Augenheilkunde
D Schmidt, G Wolff

Abstract

The case histories of two sisters with ocular infantile myasthenia are reported. The older girl has been suffering from the disease for 11 years now. Infantile myasthenia is clinically and genetically different from myasthenia gravis which occurs in older patients. The disease is probably due to a number of factors, a special genetical disposition which facilitates the specific effect of environmental factors. It cannot be ruled out, however, that in rare cases as for example in the family with parental consanguinity reported on here there is an autosomal recessive mode of transmission. The clinical and genetic heterogeneity of infantile myasthenia and the heredity of the disease are discussed.

Related Concepts

Blepharoptosis
Blepharospasm
Consanguinous Mating
Conditions, Recessive Genetic
Myasthenia Gravis, Ocular
Genealogical Tree

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