Ocular Neuromyotonia: Case Reports and Literature Review

Anne-Catherine StockmanCatherine Cassiman


Ocular neuromyotonia (ONM) is a rare eye movement disorder, presenting as a paroxysmal involuntary spasm of one or more extra-ocular muscles, that can persist for a few seconds up to several minutes. The phenomenon is caused by the contraction of an extra-ocular muscle, excited by a damaged nerve, which leads to delayed muscle relaxation. We present eight patients with this rare condition together with an overview of the literature on all published ONM cases. One of the presented cases is possibly secondary to hypovitaminosis D. This association has not been reported previously in the literature. A possible underlying mechanism is given.


Apr 1, 1975·Annals of Internal Medicine·L E MalletteW K Engel
Aug 1, 1977·Australian and New Zealand Journal of Medicine·R D Rollinson, B S Gilligan
Jul 1, 1986·Archives of Ophthalmology·W T ShultsJ J Corbett
Dec 15, 1986·American Journal of Ophthalmology·S LessellJ F Rizzo
Feb 1, 1974·Annals of Internal Medicine·B M PattenG D Aurbach
Mar 1, 1997·Archives of Ophthalmology·S M ChungO A Cruz
Oct 24, 1997·Archives of Ophthalmology·C L Haupert, N J Newman
Mar 31, 1999·Proceedings of the National Academy of Sciences of the United States of America·C M Armstrong, G Cota
Jul 13, 1999·Strabismus·A Bacskulin, R Guthoff
Sep 21, 2000·Neuromuscular Disorders : NMD·C SchneiderC R Müller
Oct 14, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·C TiliketeA Vighetto
Jul 24, 2001·Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases·C H WhitakerK J Felice
Apr 15, 2003·Clinical Neurology and Neurosurgery·Betigül Yürüten, Süleyman Ilhan
Jan 12, 2005·Archives of Ophthalmology·Michelle C BanksSimmons Lessell
Feb 25, 2005·Journal of Neurology·Maurizio VersinoVittorio Cosi
May 24, 2006·Neurology·Maud JacobCaroline Tilikete
Sep 1, 2007·Strabismus·Noa Ela-DalmanJoseph L Lasky
Apr 2, 2008·Journal of the Neurological Sciences·Hee Young ParkJi Soo Kim
Aug 19, 2008·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Alexandre de Saint SardosLuis H Ospina
Jun 6, 2009·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Jason W MuchSteven A Newman
Sep 8, 2010·Journal of Neuro-oncology·Joseph WiemelsElizabeth B Claus
Oct 7, 2010·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Daniel J Salchow, Thomas K Wermund
Sep 7, 2011·British Medical Bulletin·Mark P J Vanderpump
Nov 30, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Andrea Susan GiardinaDaniel R Eckermann
Jan 11, 2013·The New England Journal of Medicine·Sally P Stabler
May 30, 2013·Strabismus·Gill Roper-HallOscar A Cruz
Aug 22, 2015·Endocrinology, Diabetes & Metabolism Case Reports·W C Candy SzeWilliam M Drake
Mar 30, 2016·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·J Anna KimStacy L Pineles
Aug 24, 2015·Neuro-ophthalmology·Nathan H KungGregory P Van Stavern

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Dec 10, 2019·The International Journal of Neuroscience·Noha T AbokryshaRehab Magdy
May 3, 2019·JAMA Ophthalmology·Alexander GrosingerM Tariq Bhatti
Nov 5, 2020·European Journal of Ophthalmology·Cédric BallezMonique Cordonnier
Jun 16, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·J BashfordC E Shaw

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