Ocular pulse amplitude and associated glaucomatous risk factors in a healthy Hispanic population

Optometry : Journal of the American Optometric Association
Dina H EricksonJohn R Hayes

Abstract

With increasing evidence that vascular risk factors play a role in the development of glaucoma, it is critical to be familiar with factors related to intraocular blood flow, such as the ocular pulse amplitude (OPA). This study evaluates OPA and factors related to it in a healthy, Hispanic population. Refractive error, corneal curvature, Goldmann applanation tonometry (GAT), dynamic contour tonometry (DCT), OPA, axial length, and central corneal thickness (CCT) measurements were obtained on 104 Hispanic subjects recruited from the community. OPA ranged from 0.7 to 4.7 mmHg (mean, 2.1 +/- 0.8 mmHg) and showed a significant correlation with refractive error, axial length, GAT, and DCT (r=0.250, -0.358, 0.460, 0.378; P=0.011, <0.001, <0.001, and <0.001, respectively). Mean intraocular pressure with GAT was 15.6 mmHg. Mean CCT was 541.2 microm. The average refractive error was 0.75 diopters (D) of myopia, with 25% having >1.00 D myopia. Normal OPA values have not been studied in Hispanic populations. OPA is thought to provide information regarding ocular blood flow; however, more studies are needed to determine its significance in glaucoma treatment.

References

Jan 1, 1991·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·C B JamesS E Smith
Jul 17, 1991·JAMA : the Journal of the American Medical Association·J M TielschJ Javitt
Sep 1, 1985·The British Journal of Ophthalmology·E S Perkins
Oct 1, 1996·The British Journal of Ophthalmology·J H MeyerJ Funk
Mar 8, 1996·Current Opinion in Ophthalmology·A Sommer
Oct 26, 2000·The British Journal of Ophthalmology·K G SchmidtH P Hammes
May 24, 2001·The British Journal of Ophthalmology·K G SchmidtJ Flammer
Jul 6, 2002·Archives of Ophthalmology·M Cristina LeskeAnselm Hennis
Jan 4, 2003·Ophthalmology·Tien Yin WongKristine E Lee
Aug 27, 2003·Investigative Ophthalmology & Visual Science·Claude KaufmannMichael A Thiel
Apr 14, 2004·Archives of Ophthalmology·John H KempenUNKNOWN Eye Diseases Prevalence Research Group
Apr 20, 2004·Journal of Cataract and Refractive Surgery·Dimitrios S SiganosCarlos Moedas
Aug 4, 2004·Ophthalmology·Rohit VarmaUNKNOWN Los Angeles Latino Eye Study Group
Mar 10, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Mona PacheJens Funk
Mar 11, 2006·American Journal of Ophthalmology·Nathan G CongdonHarry A Quigley
Apr 28, 2006·Investigative Ophthalmology & Visual Science·Kristina Tarczy-HornochUNKNOWN Los Angeles Latino Eye Study Group
Aug 16, 2006·Archives of Ophthalmology·Claude KaufmannMichael A Thiel
Jul 14, 2007·Ophthalmology·M Cristina LeskeUNKNOWN EMGT Group
Jul 17, 2007·Ophthalmology·M Cristina LeskeUNKNOWN BESs Study Group
Dec 20, 2007·Journal of Glaucoma·Jennifer S WeizerLeon W Herndon
Jan 15, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Chantal VulstekeThierry Zeyen
Mar 26, 2008·Investigative Ophthalmology & Visual Science·Scott A ReadD Robert Iskander
Apr 29, 2008·Ophthalmology·Francis CarbonaroChris J Hammond
Jun 4, 2008·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Kirsten E HamiltonAn-Quyen Nguyen Tran
Jul 18, 2008·Acta Ophthalmologica·Ioannis HalkiadakisGerasimos Georgopoulos
Aug 16, 2008·Journal of Glaucoma·Ingeborg StalmansBrent Siesky
Oct 22, 2008·Acta Ophthalmologica·Matthias C GrieshaberSelim Orgül

❮ Previous
Next ❯

Citations

Jun 15, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Maciej CzepitaDamian Czepita
Dec 27, 2019·Journal of Glaucoma·Patrick WursterBrent Siesky

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
Martin S Zinkernagel, Andreas Ebneter
International Journal of Ophthalmology
Remzi KaradagIbrahim F Hepsen
© 2021 Meta ULC. All rights reserved