Ocular Sparganosis: The First Report of Spirometra ranarum in Thailand

The Korean Journal of Parasitology
Wilai SaksirisampantWasee Tulvatana

Abstract

A 22-year-old Thai man from the Northeast region presented with acute eye swelling, itching, and discharge on his left eye. He was suspected of having gnathostomiasis and treated with albendazole and prednisolone for 3 weeks. Nine months later, he was treated with high-dose oral prednisolone for the preliminary and differential diagnoses with thyroid-associated orbitopathy and lymphoma. He had been administered prednisolone intermittently over a few years. Then he developed a painless movable mass at the left upper eyelid and recurrent pseudotumor oculi was suspected. The surgical removal of the mass was performed. A white pseudosegmented worm revealed a definite diagnosis of ocular sparganosis by a plerocercoid larva. Molecular diagnosis of the causative species was made based on the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. Proper technique of extraction and amplification of short fragments DNA from formalin-fixed paraffin-embedded tissue successfully identified parasite species. The result from the sequencing of the PCR-amplified cox1 fragments in this study showed 99.0% sequence homology to Spirometra ranarum. This is the first report of S. ranarum in Thailand.

References

Aug 12, 2003·Parasitology Research·Surang NuchprayoonIssarang Nuchprayoon
Jul 19, 2005·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Viroj Wiwanitkit
Apr 5, 2011·Acta Tropica·Malinee T AnantaphrutiYuvadee Vanvanitchai
May 21, 2014·The American Journal of Tropical Medicine and Hygiene·Adhiratha BoonyasiriPewpan M Intapan
Jul 16, 2015·The Korean Journal of Parasitology·Hyeong-Kyu JeonKeeseon S Eom
Sep 14, 2015·The Lancet Infectious Diseases·Quan LiuXing-Quan Zhu
Sep 24, 2016·The Korean Journal of Parasitology·Hyeong-Kyu JeonKeeseon S Eom
Jun 2, 2017·JAMA Ophthalmology·Ilse MombaertsUNKNOWN Expert Panel of the Orbital Society
Jul 13, 2018·The Korean Journal of Parasitology·Hyeong-Kyu JeonKeeseon S Eom
Nov 14, 2019·The Korean Journal of Parasitology·Hyeong-Kyu Jeon, Keeseon S Eom
Jan 9, 2020·The Korean Journal of Parasitology·Keeseon S EomHyeong-Kyu Jeon

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA
PCR
electrophoresis

Software Mentioned

Geneious Program

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.