Ocular surface squamous neoplasia in an immunosuppressed patient with atopic keratoconjunctivitis.

International Ophthalmology
Thomas H FlynnStephen J Tuft

Abstract

We describe a patient with severe atopic dermatitis and keratoconjunctivitis, who was prescribed both systemic and topical ciclosporin and who developed ocular surface squamous neoplasia (OSSN). To provide additional information on the incidence of the association between topical ciclosporin use and OSSN, we counted the total prescriptions for topical ciclosporin issued in our hospital between 2003 and 2006 (804 patients) and, for the same period, we reviewed the records of patients with OSSN for a history of treatment with ciclosporin or a history of atopy. No other case of OSSN in a patient with a history of topical ciclosporin use was identified, which makes it difficult to implicate topical ciclosporin as the causative factor.

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Citations

Dec 1, 2017·Ocular Immunology and Inflammation·Lily ZhangCarol L Karp
Feb 24, 2018·Eye·Sahar ParviziAnnegret Dahlmann-Noor
Feb 10, 2018·International Ophthalmology·Swati SinghVikas Mittal
Jul 22, 2018·Ophthalmology and Therapy·Maria Vittoria CicinelliGiulio Modorati
Nov 4, 2021·Klinische Monatsblätter für Augenheilkunde·Julia BiermannFlemming Beisse

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