Ocular Toxoplasmosis in a Tertiary Referral Center in Sydney Australia-Clinical Features, Treatment, and Prognosis

Asia-Pacific Journal of Ophthalmology
William B YatesPeter J McCluskey

Abstract

The aim of this study was to provide a retrospective analysis of the presentation, demographics, and treatment regimens for ocular toxoplasmosis at a large tertiary referral uveitis center. Retrospective cohort study. A total of 48 patients with ocular toxoplasmosis who presented to Sydney Eye Hospital participated in this study. This is a retrospective review of patient files who presented to Sydney Eye Hospital between 2007 and 2016 with clinical features consistent with ocular toxoplasmosis. Baseline risk factors and treatment details were recorded and analyzed. Main outcome measures were visual acuity and relapse rate compared with other studies in ocular toxoplasmosis. The median age was 35.5 (interquartile range 21-50) with 30 (60%) patients having no previous symptomatic episodes or evidence of chorioretinal scarring. Visual acuity at presentation was 0.51 or 6/19 (SE 0.096) and at follow-up 0.31 or 6/12 (SE 0.094). Nine patients experienced a recurrence during the period of observation with median time to recurrence 2.2 years (SE 0.45) and the relapse rate was 0.09/person-years. Location of lesion was predominantly within the vascular arcades (n = 44) with macular involvement in 9 patients. Most patients received clinda...Continue Reading

References

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Citations

May 13, 2020·Expert Opinion on Drug Safety·Davide Fiore BavaroAnnalisa Saracino
Oct 30, 2020·Ophthalmic Epidemiology·Stefany Velasco-VelásquezJorge Enrique Gómez-Marín
Jan 30, 2021·Asia-Pacific Journal of Ophthalmology·Anamika PatelSoumyava Basu
Jan 30, 2021·Asia-Pacific Journal of Ophthalmology·Narsing A Rao

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