PMID: 28527170May 21, 2017Paper

Oculo-otological Manifestations in a Case of Granulomatosis with Polyangiitis

The Journal of the Association of Physicians of India
Archana SonawaleShreepriya Mangalgi

Abstract

A 44 year old lady presented with acute onset of loss of vision in the right eye and cough with mucopurulent expectoration for two months. Ophthalmic examination revealed central retinal artery occlusion (CRAO). Chest radiograph showed multiple cavitatory nodules with fluid levels. Sputum was negative for AFB and ANCA was strongly positive suggestive of a diagnosis of Granulomatosis with Polyangiitis (GPA). Within the next few weeks the patient had rapid detenoration due to left eye CRAO, progressive bilateral hearing loss, facial palsy and retro orbital mass. The aggressive disease responded well to steroids and cyclophosphamide.

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