Odor-active volatile compounds in preterm breastmilk.

Pediatric Research
Mariana MuelbertFrank H Bloomfield

Abstract

Volatile compounds in breastmilk (BM) likely influence flavor learning and, through the cephalic phase response, metabolism, and digestion. Little is known about the volatile compounds present in preterm BM. We investigated whether maternal or infant characteristics are associated with the profile of volatile compounds in preterm BM. Using solid-phase microextraction coupled with gas chromatography/mass spectrometry, we analyzed volatile compounds in 400 BM samples collected from 170 mothers of preterm infants. Forty volatile compounds were detected, mostly fatty acids and their esters (FA and FAe), volatile organic compounds (VOCs), aldehydes, terpenoids, alcohols, and ketones. The relative concentration of most FA and FAe increased with advancing lactation and were lower in BM of most socially deprived mothers and those with gestational diabetes (p < 0.05), but medium-chain FAs were higher in colostrum compared to transitional BM (p < 0.001). Infant sex, gestational age, and size at birth were not associated with the profile of volatile compounds in preterm BM. Sensory-active volatile FA and FAe are the major contributors to the smell of preterm BM. The associations between lactation stage, maternal characteristics, and volat...Continue Reading

References

Sep 1, 1994·The American Journal of Clinical Nutrition·M B JacksonA M Ferris
Jul 1, 1993·The American Journal of Clinical Nutrition·S H NeubauerK W Green
Dec 13, 2000·Chemical Senses·B SchaalR Soussignan
Jan 5, 2002·Early Human Development·M RamírezA Gil
Oct 15, 2003·Archives of Pediatrics & Adolescent Medicine·Peter M BinghamTerri Acree
Feb 28, 2004·Environment International·F FabiettiM R Sprechini
Jun 16, 2006·European Journal of Clinical Nutrition·Y Y Al-Tamer, A A Mahmood
Apr 3, 2007·Environmental Science & Technology·Sung R KimTimothy J Buckley
Apr 5, 2007·Acta Paediatrica·Chantal RaimbaultRichard H Porter
Jul 17, 2009·The American Journal of Clinical Nutrition·Julie A MennellaGary K Beauchamp
Feb 25, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Susanne Lindquist, Olle Hernell
Apr 2, 2010·Journal of Environmental Monitoring : JEM·Benjamin C BlountJudy S Lakind
Aug 3, 2010·Early Human Development·Shiori AoyamaMasao Kobayashi
Oct 22, 2010·Nutrition Reviews·Paul A M SmeetsCees de Graaf
Oct 28, 2010·International Breastfeeding Journal·Ingunn Ms EngebretsenJames K Tumwine
Feb 22, 2011·Archives of Oral Biology·Chifu B HuangJeffrey L Ebersole
Dec 1, 2011·Journal of Clinical Biochemistry and Nutrition·Ingrid Elisia, David D Kitts
May 1, 2012·Journal of Dairy Science·C Ramírez-SantanaA Franch
Feb 26, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Johanna SpitzerAndrea Buettner
Sep 1, 2007·Metabolomics : Official Journal of the Metabolomic Society·Lloyd W SumnerMark R Viant
Oct 10, 2013·American Journal of Human Biology : the Official Journal of the Human Biology Council·Sagar K ThakkarFrédéric Destaillats
Sep 2, 2014·BMC Pediatrics·Dominica A Gidrewicz, Tanis R Fenton
Feb 25, 2015·Nature Reviews. Endocrinology·Sara Santa-Cruz Calvo, Josephine M Egan
Jul 30, 2015·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Hadar Moran-LevRonit Lubetzky
Feb 13, 2016·Lancet·Cesar G VictoraUNKNOWN Lancet Breastfeeding Series Group
Jan 28, 2017·Environment International·Peder Wolkoff, Gunnar D Nielsen
Mar 25, 2017·Nutrition·Ilana R Azulay ChertokNurit Argov-Argaman
Dec 1, 2015·Food Research International·M GarridoR Ramírez
May 19, 2017·The American Journal of Clinical Nutrition·Julie A MennellaAshley R Reiter
Aug 24, 2017·The British Journal of Nutrition·Elizabeth Sosa-CastilloCarolina Moltó-Puigmartí
Sep 2, 2017·Journal of Human Lactation : Official Journal of International Lactation Consultant Association·Irma PreustingJudette M Louis
Mar 15, 2018·Journal of Inherited Metabolic Disease·Ilya Gertsman, Bruce A Barshop
Mar 20, 2018·Best Practice & Research. Clinical Endocrinology & Metabolism·Hans Demmelmair, Berthold Koletzko
Jun 14, 2018·Physiological Reviews·Désirée Maßberg, Hanns Hatt
Dec 31, 2018·Journal of Dairy Science·Dimitra MastorakouMarkus Stieger
Mar 13, 2019·Pediatric Research·Jennifer Hahn-HolbrookLaura Glynn
Mar 29, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Dana ShapiraRonit Lubetzky
May 17, 2019·Journal of Pediatric Gastroenterology and Nutrition·Alexandre LapillonneUNKNOWN ESPGHAN Committee on Nutrition
Jul 17, 2019·The Cochrane Database of Systematic Reviews·Mariana MuelbertJane E Harding
Aug 17, 2019·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Li WenPhilip Baker
Aug 20, 2019·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Isabell NesselSimon C Dyall
Oct 6, 2019·Scientific Reports·Laura GalanteShikha Pundir

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.