Odor supported place cell model and goal navigation in rodents.

Journal of Computational Neuroscience
Tomas KulviciusFlorentin Wörgötter

Abstract

Experiments with rodents demonstrate that visual cues play an important role in the control of hippocampal place cells and spatial navigation. Nevertheless, rats may also rely on auditory, olfactory and somatosensory stimuli for orientation. It is also known that rats can track odors or self-generated scent marks to find a food source. Here we model odor supported place cells by using a simple feed-forward network and analyze the impact of olfactory cues on place cell formation and spatial navigation. The obtained place cells are used to solve a goal navigation task by a novel mechanism based on self-marking by odor patches combined with a Q-learning algorithm. We also analyze the impact of place cell remapping on goal directed behavior when switching between two environments. We emphasize the importance of olfactory cues in place cell formation and show that the utility of environmental and self-generated olfactory cues, together with a mixed navigation strategy, improves goal directed navigation.

References

Sep 1, 1989·Behavioural Brain Research·D Eilam, I Golani
Jan 1, 1987·Experimental Brain Research·J O'Keefe, A Speakman
Jun 1, 1986·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·T S CollettB A Smith
May 1, 1984·Journal of Neuroscience Methods·R Morris
Mar 1, 1980·Canadian Journal of Psychology·C A BarnesW K Honig
Aug 20, 1993·Science·M A Wilson, B L McNaughton
Dec 1, 1995·Physiology & Behavior·P Lavenex, F Schenk
Apr 1, 1996·Current Opinion in Neurobiology·R U MullerJ S Taube
Jan 1, 1996·Hippocampus·D S Touretzky, A D Redish
Dec 16, 1998·Animal Behaviour·P Lavenex, F Schenk
Jan 9, 1999·Hippocampus·N Brunel, O Trullier
Aug 12, 1999·Experimental Brain Research·K J Jeffery, J M O'Keefe
Aug 18, 2001·Behavioral Neuroscience·P A Dudchenko
Jan 5, 2002·Journal of Neuroscience Methods·Douglas G WallaceIan Q Whishaw
Feb 15, 2002·Behavioural Brain Research·Douglas G WallaceIan Q Whishaw
Jun 14, 2003·Behavioral Neuroscience·Douglas G WallaceIan Q Whishaw
Sep 12, 2003·Nature·Arne D EkstromItzhak Fried
Sep 30, 2003·Reviews in the Neurosciences·Christian Hölscher
Mar 24, 2004·The Journal of Experimental Biology·Ariane S EtienneTiffany Rowe
Apr 22, 2004·Hippocampus·Ariane S Etienne, Kathryn J Jeffery
May 14, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Francesco P BattagliaBruce L McNaughton
Sep 24, 2004·IEEE Transactions on Neural Networks·Angelo ArleoWulfram Gerstner
Jun 21, 2005·Nature·Torkel HaftingEdvard I Moser
Aug 4, 2005·Neuroinformatics·Ricardo ChavarriagaWulfram Gerstner

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Citations

May 1, 2008·Journal of Computational Neuroscience·Minija TamosiunaiteFlorentin Wörgötter
Jul 29, 2016·Cognitive Neurodynamics·Chuankui YanGuanrong Chen
Sep 2, 2016·Wiley Interdisciplinary Reviews. Cognitive Science·Vincent HokFrancesca Sargolini
Apr 26, 2018·Frontiers in Systems Neuroscience·Mikhail A Lebedev, Alexei Ossadtchi
Mar 10, 2018·Frontiers in Neuroanatomy·Afif J Aqrabawi, Jun Chul Kim
Jun 21, 2018·Frontiers in Neuroscience·Yihong WangRubin Wang
Feb 17, 2018·Learning & Memory·Daniel G McHailTheodore C Dumas
Jul 3, 2021·Neuroscience and Biobehavioral Reviews·Clara U Raithel, Jay A Gottfried

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