PMID: 2508306Jan 1, 1989Paper

Oesophageal squamous cell carcinoma with lymphoid stroma. A case report

Virchows Archiv. A, Pathological Anatomy and Histopathology
M MoriK Sugimachi

Abstract

We treated a 70-year-old Japanese man with squamous cell carcinoma of the oesophagus with evidence of lymphoid stroma. The tumour consisted of a main lesion invading the muscular layer of the oesophagus, in association with wide areas of carcinoma in situ. The tumour stroma of the lesion was nondesmoplastic and was uniformly infiltrated mainly by abundant lymphocytes and plasma cells. Immunohistochemically, the lymphocytes consisted of a large number of T lymphocytes and a small number of B lymphocytes. S-100 protein positive cells were marked in the tumour cell nests and necrotic change of tumour cells was frequent. Abundant infiltration of lymphocytes and plasma cells was also wide-spread beneath the carcinoma in situ, together with the lymphoid follicles. Carcinoma with lymphoid stroma can occur not only in the breast, uterine cervix, nasopharynx and stomach but also in the oesophagus.

References

Apr 1, 1978·Cancer·F V Lucas, C Perez-Mesa
Feb 1, 1988·American Journal of Clinical Pathology·M SantamariaS M Hsu
Jan 1, 1980·Immunological Reviews·G StinglS I Katz
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Apr 1, 1982·The Journal of Experimental Medicine·W C Van VoorhisG Kaplan

❮ Previous
Next ❯

Citations

Jun 29, 1999·Surgery Today·T YamadaH Matsunou
Aug 7, 2003·The Annals of Thoracic Surgery·Freddy Angulo-Pernett, W Roy Smythe
May 23, 2002·The American Journal of Surgical Pathology·Yih-Leong ChangYung-Chie Lee
Jul 27, 2001·Journal of Clinical Gastroenterology·K Takubo, N K Lambie
Nov 23, 2007·Journal of Gastroenterology and Hepatology·Masahiko NakasonoToshiaki Sano
Jun 1, 1996·Journal of Clinical Pathology·W K NgY L Kwong
May 2, 2007·Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B·José Rafael ValbuenaAlejandro Corvalan
Jun 29, 1999·Journal of Gastroenterology and Hepatology·H SashiyamaK Ozawa
Jan 25, 2000·Japanese Journal of Clinical Oncology·K ShimizuY Heike

❮ Previous
Next ❯

Related Concepts

Related Feeds

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.