Offline telepathology diagnosis of colorectal polyps: a study of interobserver agreement and comparison with glass slide diagnoses

Journal of Clinical Pathology
S S CrossR D Start

Abstract

Technological advances have produced telepathology systems with high quality colour images and reasonable transmission times. Most applications of telepathology have centred on the remote diagnosis of frozen sections or remote real time expert opinions. This study investigates the reproducibility and accuracy of offline telepathology as a primary diagnostic medium for routine histopathology specimens. One hundred colorectal polyps (50 hyperplastic, 50 adenomatous) were presented in a randomised order to five histopathologists as offline images on a telepathology workstation. Six images of each case were used: the slide label, a low power scan of all material on the slide, and four higher magnification views. The times taken to prepare the images, and to make the diagnoses, were recorded. Interobserver agreement was measured with kappa statistics and compared with the glass slide diagnoses. The kappa statistics for the interobserver agreement on the telepathology images lay in the range of 0.90-1.00, which is interpreted as excellent agreement, and were significantly higher than those for the glass slide diagnoses (range, 0.84-0.98; p = 0.001). The median time taken to capture the images for a case was 210 seconds. The median ti...Continue Reading

References

Jan 1, 1997·Human Pathology·R S WeinsteinJ R Davis
Jan 1, 1997·Human Pathology·V EusebiJ Rosai
Jan 1, 1997·Human Pathology·M H Weinstein, J I Epstein
Oct 8, 1998·Histopathology·S S Cross
Feb 16, 2000·Journal of Clinical Pathology·V Della MeaC A Beltrami
Apr 18, 2000·The Journal of Pathology·C A Wells, C Sowter
Aug 3, 2000·Human Pathology·J ZhouT S Nesbitt
Aug 16, 2000·Radiologic Clinics of North America·D B Kopans
Aug 30, 2000·Virchows Archiv : an International Journal of Pathology·U WellnitzP Schwarzmann
Sep 28, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·S S CrossT J Stephenson
Nov 18, 2000·Archives of Pathology & Laboratory Medicine·A MarceloH Cualing

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Citations

May 27, 2003·The American Journal of Surgical Pathology·Peter N FurnessRafail Rosenthal
Dec 13, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Sean A SukalKishwer S Nehal
May 21, 2010·Cytopathology : Official Journal of the British Society for Clinical Cytology·A Evered, N Dudding
Jul 23, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Femi LasisiDouglas K Rex
Jun 25, 2009·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Ekaterina Kldiashvili, Thomas Schrader
Aug 22, 2009·European Journal of Gastroenterology & Hepatology·Bernard DenisJean François Fléjou
Oct 31, 2009·Journal of Applied Genetics·I BrozekJ Limon
Jan 28, 2004·Human Pathology·Ivar NordrumJon Arne Ludvigsen

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